Katari Sudheer Kumar
Sri Venkateswara Institute of Medical Sciences
5 Papers
17 Citations
Katari Sudheer Kumar is an academic researcher from Sri Venkateswara Institute of Medical Sciences. The author has contributed to research in topics: Docking (molecular) & Pharmacophore. The author has an hindex of 3, co-authored 4 publications.
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Papers
197 Combination of e-pharmacophore modeling, multiple docking strategies and molecular dynamic simulations to discover of novel antagonists of BACE1
Natarajan Pradeep,Manne Munikumar,Sandeep Swargam,Kanipakam Hema,Katari Sudheer Kumar,Amineni Umamaheswari +5 more
TL;DR: Antiinflamatory activity of phenolic compounds extracted from Uruguayan propolis and grape Elena Alvareda*, Pablo Miranda, Victoria Espinosa, Helena Pardo, Sara Aguilera and Margot Paulino Zunini.
18
Inhibitor Design for VacA Toxin of Helicobacter pylori
Pasala Chiranjeevi,eep Swargam,Natarajan Pradeep,Kanipakam Hema,Katari Sudheer Kumar,Nalamolu Ravina Madhulitha,Amineni Umamaheswari +6 more
TL;DR: The proposed leads represent novel valuable starting point in the development of inhibitor to VacA, an important unique virulence factor in the pathogenesis of Helicobacter pylori.
11
Identification of a natural antagonist for signal transducer and activator of transcription 3 (STAT3) by computational approach
Katari Sudheer Kumar,Amineni Umamaheswari,Dinesh Lakhanpal,Sandeep Swargam,Khateef Riazunnisa,V. Chandrasekar +5 more
TL;DR: In this paper , the authors designed novel antagonists against STAT3 using phytocompounds of two medicinal plants (Catharanthus roseus and Moringa oleifera) by integration of in-vivo and in-silico strategy.
3
Synthesis, Molecular Docking Studies and Biological Evaluation of N-Acylarylhydrazones as Anti-Inflammatory Agents.
TL;DR: A series of N'-arylidene-2-(benzamido)-3-(naphthalen-2-yl)acrylohydrazides were synthesized by refluxing the intermediate 2-phenyloxazol-5(4H)-one with hydrazine hydrate in the presence of absolute ethanol, and were found to be more active than standard drug phenylbutazone at equidose.
E-Pharmacophore Model Assisted Discovery of Novel Antagonists ofnNOS
Nalamolu Ravina Madhulitha,Natarajan Pradeep,Sandeep Swargam,eep,Kanipakam Hema,Pasala Chiranjeevi,Katari Sudheer Kumar,Amineni Umamaheswari +7 more
TL;DR: Three leads are proposed having favorable absorption distribution metabolism excretion toxicity (ADME/T) properties and provide a scaffold for designing nNOS antagonists and are proposed to be one of the revitalizing targets for AD.