Karoly Nikolics
United States Department of Veterans Affairs
6 Papers
48 Citations
Karoly Nikolics is an academic researcher from United States Department of Veterans Affairs. The author has contributed to research in topics: Peptide & Cerebellum. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Karoly Nikolics include Eötvös Loránd University & Tulane University.
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Papers
Distribution of 3H-α-MSH in rat brain
Abba J. Kastin,Abba J. Kastin,Abba J. Kastin,Cheryl Nissen,Cheryl Nissen,Cheryl Nissen,Karoly Nikolics,Karoly Nikolics,Karoly Nikolics,Kalmen Medzihradszky,Kalmen Medzihradszky,Kalmen Medzihradszky,David H. Coy,David H. Coy,David H. Coy,Istvan Teplan,Istvan Teplan,Istvan Teplan,Andrew V. Schally,Andrew V. Schally,Andrew V. Schally +20 more
TL;DR: Radioactive synthetic α-MSH, prepared by selective tritiation of its dibromo-L-tyrosine2-derivative, was injected into the carotid artery of intact, hypophysectomized or pinealectomized rats, finding large amounts of radioactivity in the pituitary and in the pineal.
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Disappearance and excretion of labeled α-MSH in man☆
Tommie W. Redding,Tommie W. Redding,Abba J. Kastin,Abba J. Kastin,Karoly Nikolics,Karoly Nikolics,Andrew V. Schally,Andrew V. Schally,David H. Coy,David H. Coy +9 more
TL;DR: The results suggest that the persistence of high levels of α-MSH in the blood after injection in man may be too short to fully explain the CNS effects ofα- MSH.
19
Patent
Gonadoliberin derivatives process for the preparation and pharmaceutical compositions thereof
Ferenc A. Antoni,Erchegyi Judit,Aniko Horvath,Gyorgy Keri,Imre Mezo,Karoly Nikolics,Janos Seprodi,Andras Szell,Balazs Szoke,Istvan Teplan +9 more
- 25 May 1983
TL;DR: In this article, new gonadoliberin derivatives of the formula (I) Glp-His-Trp-Ser-Tyr-X-Leu-Arg-Pro-Y, where Y represents a glycine-amide group or an -NH-alkyl group having 1 to 4 carbon atoms in the alkyl moiety, X stands for a D-thyroxyl, Dthyronyl or D-4-chlorophenylalanyl group, and acid addition salts and metal complexes thereof.
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Isolation and Characterization of Two Peptides with Prolactin Release- Inhibiting Activity from Porcine Hypothalami
Andrew V. Schally,Janos G. Guoth,Tommie W. Redding,Kate Groot,Henry Rodriguez,Eva Szonyi,John T. Stults,Karoly Nikolics +7 more
TL;DR: Two peptides with in vitro prolactin release-inhibiting activity were purified from stalk median eminence fragments of 20,000 pig hypothalami to apparent homogeneity as judged by the UV absorbance profiles.
10
Patent
Gonadoliberin derivatives, process for the preparation and pharmaceutical and veterinary compositions thereof
Ferenc A. Antoni,Erchegyi Judit,Aniko Horvath,Gyorgy Keri,Imre Mezo,Karoly Nikolics,Janos Seprodi,Andras Szell,Balazs Szoke,Istvan Teplan +9 more
- 25 May 1983
TL;DR: New gonadoliberin derivatives of the formula Glp-His-Trp-Ser-Tyr-X-Lev-Arg-Pro-Y, wherein Y represents glycineamide group or an -NH-alkyl group having 1 to 4 carbon atoms in the alkyl moiety, X stands for a D-tyroxyl, D -tyronyl or D-4-chlorophenyl-alanyl group, and acid addition salts and metal complexes thereof, have an excellent luteinizing and folliculus stimulating hormone releasing activity as discussed by the authors.
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