Karin Wind-Mark
16 Papers
Karin Wind-Mark is an academic researcher. The author has contributed to research in topics: Microglia & Medicine. The author has an hindex of 1, co-authored 10 publications.
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Papers
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models
Bettina van Lengerich,Lihong Zhan,Dan Xia,Darren K.W. Chan,David A Joy,Joshua I. Park,David Tatarakis,Meredith E. K. Calvert,Selina Hummel,Steve Lianoglou,Michelle E. Pizzo,Rachel Prorok,Elliot R. Thomsen,L. Bartos,Philipp Beumers,Anja Capell,Sonnet S. Davis,Lis de Weerd,Jason C. Dugas,Joseph N. Duque,Timothy K. Earr,Kapil Gadkar,Tina Giese,Audrey Gill,Johannes Gnörich,Connie Ha,Malavika Kannuswamy,Do Jin Kim,Sebastian T Kunte,L. Kunze,Diana Lac,Kendra J. Lechtenberg,Amy Wing-Sze Leung,Chun-Chi Liang,Isabel Lopez,Paul V. McQuade,Anuja Modi,Vanessa O Torres,Hoang Nguyen,Ida Pesämaa,Nicholas E. Propson,Marvin Reich,Yaneth Robles-Colmenares,Kai Schlepckow,L. Slemann,Hilda Solanoy,Jung H. Suh,Robert G. Thorne,Chandler Vieira,Karin Wind-Mark,Ken Xiong,Y. Joy Yu Zuchero,Dolo Diaz,Mark S. Dennis,Fen Huang,Kimberly Scearce-Levie,Ryan J. Watts,Christian Haass,Joseph W. Lewcock,Gilbert Di Paolo,Matthias Brendel,Pascal E. Sanchez,Kathryn M. Monroe +62 more
TL;DR: A high affinity human TREM2-activating antibody engineered with a monovalent transferrin receptor (TfR) binding site, termed antibody transport vehicle (ATV), was used to facilitate blood-brain barrier transcytosis as mentioned in this paper .
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution
L. Bartos,S V Kirchleitner,Z. I. Kolabas,S. Quach,Jens Blobner,Stephan A Mueller,Selin Ulukaya,Luciano Hoeher,Izabela Horvath,Karin Wind-Mark,Adrien Holzgreve,Viktoria Ruf,L. Gold,L. Kunze,Sebastian T Kunte,Philipp Beumers,M. Antons,A.V Zatcepin,Nils Briel,Leonie Hoermann,Denise Messerer,Peter Bartenstein,Markus J. Riemenschneider,Simon Lindner,Sibylle Ziegler,Jochen Herms,Stefan F. Lichtenthaler,Ali Ertürk,Jörg C. Tonn,Louisa von Baumgarten,Nathalie L. Albert,Matthias Brendel +31 more
TL;DR: In this paper , the authors developed immunomagnetic cell sorting after in vivo radiotracer injection (scRadiotracing) in combination with 3D-histology via tissue clearing to dissect the cellular allocation of PET signals in the tumor microenvironment.
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Longitudinal Studies on Alzheimer Disease Mouse Models with Multiple Tracer PET/CT: Application of Reduction and Refinement Principles in Daily Practice to Safeguard Animal Welfare during Progressive Aging
G. Palumbo,L. Kunze,Rosel Oos,Karin Wind-Mark,Simon Lindner,Barbara von Ungern-Sternberg,Peter Bartenstein,Sibylle Ziegler,Matthias Brendel +8 more
TL;DR: In this paper , a daily practice focused on the improvement of animal welfare (such as handling, enriched environment, study design, and experimental procedures) results in a weight gain over time that has been shown to be an indicator of well-being.
Microglia drive TSPO PET signal increases in a tauopathy mouse model
L. Bartos,Carla Palleis,Stephen Hummel,Lennart Schlaphoff,L. Kunze,Karin Wind-Mark,Simon Lindner,Peter Bartenstein,S. Ziegler,NL Albert,JD Levin,Maike Brendel +11 more
TL;DR: Ziel/Aim Tau and 18 kDa translocator protein (TSPO) PET signals progress jointly during the continuum of neurodegenerative diseases, but it remains unclear if increasing TSPO PET signals dominantly reflect activated microglia or reactive astrocytes as discussed by the authors .
Tumoral translocator protein expression is associated with microglia-related whole brain inflammation in glioblastoma
Stephanie Quach,S V Kirchleitner,Jutta Blobner,Sebastian T Kunte,Philipp Beumers,Karin Wind-Mark,Adrien Holzgreve,Peter Bartenstein,JC Tonn,Louisa von Baumgarten,Maike Brendel,NL Albert +11 more
TL;DR: In this article , the translational TSPO PET imaging was used to investigate whole brain inflammation in therapy-naïve glioma, and the presence of remote neuroinflammation was only sparsely understood.