Karin Nunley
University of Colorado Denver
20 Papers
320 Citations
Karin Nunley is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Population & Gene expression. The author has an hindex of 14, co-authored 20 publications. Previous affiliations of Karin Nunley include University of Colorado Boulder & Anschutz Medical Campus.
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Papers
Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.
Lawrence D. Snell,Karin Nunley,Ronald Lickteig,Michael Browning,Boris Tabakoff,Paula L. Hoffman +5 more
TL;DR: It is demonstrated that chronic ethanol ingestion by mice, which results in the generation of physical dependence, also produces increases in the NMDA receptor NR1 subunit protein in the hippocampus and cerebellum, and produces rises in the NR2A subunitprotein inThe hippocampus and cortex, however, the mRNA levels for these subunits were not increased in the respective brain areas by the same ethanol treatment.
193
Beta-adrenergic adaptation in paediatric idiopathic dilated cardiomyopathy.
Shelley D. Miyamoto,Brian L. Stauffer,Brian L. Stauffer,Stephanie J. Nakano,Rebecca D. Sobus,Karin Nunley,Penny Nelson,Carmen C. Sucharov +7 more
TL;DR: There is a different adaptation of β-AR and adrenergic signalling pathways in children with HF compared with adults, and this research suggests that age-related differences in adaptation could influence the response to therapy.
120
Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction.
TL;DR: Differentially regulated miRNAs are predicted to target expression of several genes in multiple biological processes involved in the response to MI and a combinatorial analysis of mRNA and miRNA expression may aid in determining factors involved in compensatory and decompensated responses to cardiac injury.
45
Simultaneous quantification of human cardiac alpha- and beta-myosin heavy chain proteins by MALDI-TOF mass spectrometry
Steve M. Helmke,Chia-Yu Yen,Krzysztof J. Cios,Karin Nunley,Michael R. Bristow,Mark W. Duncan,M. Benjamin Perryman +6 more
TL;DR: A novel method for quantifyingprotein isoforms, in both relative and absolute terms, based on MALDI-TOF mass spectrometry is developed, demonstrated by quantifying the α and β protein isoforms of myosin heavy chain in human atrial tissue.
44
The PPAR-α activator fenofibrate fails to provide myocardial protection in ischemia and reperfusion in pigs
Ya Xu,Li Lu,Clifford R. Greyson,Mona Rizeq,Karin Nunley,Beata Wyatt,Michael R. Bristow,Carlin S. Long,Gregory G. Schwartz +8 more
TL;DR: Despite expression of PPar-alpha in porcine myocardium and effects of fenofibrate on systemic metabolism, treatment with this PPAR-alpha activator does not alter myocardial metabolic or contractile responses to I/R in pigs.