Karin Ledolter
University of Vienna
9 Papers
92 Citations
Karin Ledolter is an academic researcher from University of Vienna. The author has contributed to research in topics: Methyl group & Parkinson's disease. The author has an hindex of 4, co-authored 6 publications.
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Papers
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Wolfgang Wrasidlo,Igor F. Tsigelny,Diana L. Price,Garima Dutta,Edward Rockenstein,Thomas C. Schwarz,Karin Ledolter,Douglas W. Bonhaus,Amy Paulino,Simona Eleuteri,Åge A. Skjevik,Åge A. Skjevik,Valentina L. Kouznetsova,Brian Spencer,Paula Desplats,Tania Gonzalez-Ruelas,Margarita Trejo-Morales,Cassia R. Overk,Stefan Winter,Chunni Zhu,Marie-Françoise Chesselet,Dieter Meier,Herbert Moessler,Robert Konrat,Eliezer Masliah +24 more
TL;DR: The notion that altering the interaction of α-synuclein with the membrane might be a feasible therapeutic approach for developing new disease-modifying treatments of Parkinson's disease and other synucleinopathies is supported.
Synthesis of a 13C-Methyl-Group-Labeled Methionine Precursor as a Useful Tool for Simplifying Protein Structural Analysis by NMR Spectroscopy
TL;DR: A novel synthetic route towards a precursor of the S-C-methyl-bearing amino acid, methionine is reported, which is a biosynthetic precursors for the aliphatic amino acids isoleucine, as well as leucine and valine, respectively.
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Oxidation of naringenin by gamma-radiation
TL;DR: In this paper, the reaction of OH with naringenin (4′,5,7-trihydroxyflavanone) in the presence of air induced the formation of the hydroxylation product eriodictyol (3′,4, 5, 7-tetrahydroxy flavanone).
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Direct methods and residue type specific isotope labeling in NMR structure determination and model-driven sequential assignment
Andreas Schedlbauer,Renate Auer,Karin Ledolter,Martin Tollinger,Karin Kloiber,Roman J. Lichtenecker,Simon Ruedisser,Ulrich Hommel,Walther Schmid,Robert Konrat,Georg Kontaxis +10 more
TL;DR: In a hybrid approach these ambiguous models have the potential to aid in the process of sequential backbone chemical shift assignment when 13Cβ and 13C′ shifts are not available for sensitivity reasons and enhance the information content of the NOE spectra.
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