Karen C. Thomas
University of Utah
13 Papers
71 Citations
Karen C. Thomas is an academic researcher from University of Utah. The author has contributed to research in topics: Pharmacy & Medicine. The author has an hindex of 7, co-authored 12 publications.
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Papers
Transient Receptor Potential Vanilloid 1 Agonists Cause Endoplasmic Reticulum Stress and Cell Death in Human Lung Cells
Karen C. Thomas,Ashwini S. Sabnis,Mark E. Johansen,Diane L. Lanza,Philip J. Moos,Garold S. Yost,Christopher A. Reilly +6 more
TL;DR: It is concluded that activation of ER-bound TRPV1 and stimulation of GADD153 expression via the EIF2 αK3/EIF2α pathway represents a common mechanism for cytotoxicity by cell-permeable TRpV1 agonists.
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Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury
Karen C. Thomas,Jessica K. Roberts,Cassandra E. Deering-Rice,Erin G. Romero,Randal O. Dull,Jeewoo Lee,Garold S. Yost,Christopher A. Reilly +7 more
TL;DR: Testing the hypothesis that endovanilloids produced following lipopolysaccharide (LPS) treatment activate TRPV1 and cause endoplasmic reticulum stress/GADD153 expression in lung cells, representing a mechanistic component of lung injury demonstrates that ER stress and cytotoxicity are not essential for pulmonary edema.
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•Journal Article
Buprenorphine prescribing practices and exposures reported to a poison center - Utah, 2002-2011
TL;DR: Increased buprenorphine prescribing in Utah during 2002-2011 likely represents expanded access to critically needed opioid addiction treatment; however, safeguards should be in place to prevent adverse effects.
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Implementation and quality assessment of a pharmacy services call center for outpatient pharmacies and specialty pharmacy services in an academic health system.
TL;DR: The design and implementation of a pharmacy services call center for outpatient pharmacies and specialty pharmacy services within an academic health system have significantly improved the health system’s patient experiences, efficiency, and quality.
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Development and implementation of a centralized comprehensive refill authorization program in an academic health system.
TL;DR: Implementation of an integrated refill authorization service standardized the method by which patients’ refill requests were addressed, increased refill efficiency, and improved refill authorization turnaround time.
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