Kana Miyamoto
Keio University
64 Papers
206 Citations
Kana Miyamoto is an academic researcher from Keio University. The author has contributed to research in topics: Osteoclast & Osteoporosis. The author has an hindex of 26, co-authored 56 publications. Previous affiliations of Kana Miyamoto include Toho University & Kumamoto University.
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Papers
Regulation of Reactive Oxygen Species by Atm Is Essential for Proper Response to DNA Double-Strand Breaks in Lymphocytes
Keisuke Ito,Keiyo Takubo,Fumio Arai,Hitoshi Satoh,Sahoko Matsuoka,Masako Ohmura,Masako Ohmura,Kazuhito Naka,Masaki Azuma,Kana Miyamoto,Kentaro Hosokawa,Yasuo Ikeda,Tak W. Mak,Toshio Suda,Atsushi Hirao +14 more
TL;DR: Atm-mediated ROS regulation is essential for proper DNA recombination, preventing immunodeficiency, and lymphomagenesis, and in vivo administration of NAC to Atm−/− mice restored normal T cell development and inhibited aberrant V(D)J recombination.
MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner.
Kana Miyamoto,Ken Ninomiya,Koh Hei Sonoda,Yoshiteru Miyauchi,Hiroko Hoshi,Ryotaro Iwasaki,Hiroya Miyamoto,Shigeyuki Yoshida,Yuiko Sato,Hideo Morioka,Kazuhiro Chiba,Kensuke Egashira,Toshio Suda,Yoshiaki Toyama,Takeshi Miyamoto +14 more
TL;DR: It is described that multinuclear osteoclast formation was significantly inhibited in cells derived from MCP-1-deficient mice, indicating that osteOClastogenesis was regulated in an autocrine/paracrine manner by MCP -1 under the stimulation of RANKL in osteoclasts.
Osteonecrosis development by tooth extraction in zoledronate treated mice is inhibited by active vitamin D analogues, anti-inflammatory agents or antibiotics
Tomoya Soma,Ryotaro Iwasaki,Yuiko Sato,Tami Kobayashi,Eriko Ito,Tatsuaki Matsumoto,Atsushi Kimura,Kana Miyamoto,Morio Matsumoto,Masaya Nakamura,Mayu Morita,Seiji Asoda,Hiromasa Kawana,Taneaki Nakagawa,Takeshi Miyamoto +14 more
TL;DR: In this paper , the authors show that in mice, administration of either active vitamin D analogues, antibiotics or anti-inflammatory agents can prevent osteonecrosis of the jaw (ONJ) induced by tooth extraction during treatment with bisphosphonate zoledronate.
Hyperglycemia Promotes Schwann Cell De-differentiation and De-myelination via Sorbitol Accumulation and Igf1 Protein Down-regulation.
Wu Hao,Syoichi Tashiro,Tomoka Hasegawa,Yuiko Sato,Tami Kobayashi,Toshimi Tando,Eri Katsuyama,Atsuhiro Fujie,Ryuichi Watanabe,Mayu Morita,Kana Miyamoto,Hideo Morioka,Masaya Nakamura,Morio Matsumoto,Norio Amizuka,Yoshiaki Toyama,Takeshi Miyamoto +16 more
TL;DR: It is reported that Schwann cells de-differentiate into immature cells under hyperglycemic conditions as a result of sorbitol accumulation and decreased Igf1 expression in those cells.
Cell fusion in osteoclasts plays a critical role in controlling bone mass and osteoblastic activity
Ryotaro Iwasaki,Ken Ninomiya,Kana Miyamoto,Toru Suzuki,Yuiko Sato,Hiromasa Kawana,Taneaki Nakagawa,Toshio Suda,Takeshi Miyamoto +8 more
TL;DR: Results indicate that inhibition of a single molecule provides both decreased osteoclast activity and increased bone formation by osteoblasts, thereby increasing bone mass in an un-coupled and a tissue specific manner.