Kan Kaneko
Liverpool John Moores University
13 Papers
19 Citations
Kan Kaneko is an academic researcher from Liverpool John Moores University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 10 publications. Previous affiliations of Kan Kaneko include University of Otago.
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Papers
An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery.
Kailash C. Petkar,Suyash M. Patil,Sandip S. Chavhan,Kan Kaneko,Krutika K. Sawant,Nitesh K. Kunda,Imran Saleem +6 more
TL;DR: In this paper, a review article summarizes nanoscale-based adjuvants and delivery vehicles such as viral vectors, virus-like particles and virosomes; non-viral vectors namely nanoemulsions, lipid nanocarriers, biodegradable and non-degradable nanoparticles, calcium phosphate nanoparticles and colloidally stable nanoparticles; and pattern recognition receptors covering c-type lectin receptors and toll-like receptors.
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Evaluation of polymer choice on immunogenicity of chitosan coated PLGA NPs with surface-adsorbed pneumococcal protein antigen PspA4Pro.
Kan Kaneko,Eliane N. Miyaji,Viviane Maimoni Gonçalves,Daniela M. Ferreira,Carla Solórzano,Ronan MacLoughlin,Imran Saleem +6 more
TL;DR: This paper investigated variations for making chitosan-coated polymeric nanoparticles (NPs) incorporating recombinant pneumococcal surface protein A from family 2, clade 4 (PspA4Pro) antigen as a vaccine, and determined the effect of the polymers on particle size, surface charge, and surface marker upregulation on a dendritic cell line in vitro.
14
Characterization and evaluation of stabilized particulate formulations as therapeutic oral vaccines for allergy.
TL;DR: The generated responses did not exhibit tolerogenic traits which could be useful for immunoregulation, but the responses generated varied between formulations and suggests that further characterization and optimization could lead to the desired immune response.
13
In Vitro Characterization of Inhalable Cationic Hybrid Nanoparticles as Potential Vaccine Carriers
Iman M. Alfagih,Iman M. Alfagih,Kan Kaneko,Nitesh K. Kunda,Nitesh K. Kunda,Fars K. Alanazi,Sarah R. Dennison,Hesham M. Tawfeek,Imran Saleem +8 more
TL;DR: In this paper, PGA-co-PDL nanoparticles (NPs) encapsulating model antigen, bovine serum albumin (BSA), were prepared via double emulsion solvent evaporation.
12
Progress in mucosal immunization for protection against pneumococcal pneumonia.
Viviane Maimoni Gonçalves,Kan Kaneko,Carla Solórzano,Ronan MacLoughlin,Imran Saleem,Eliane N. Miyaji +5 more
TL;DR: The most promising delivery systems are based on nanoparticles, bacterial-like particles or nanogels, which possess greater immunogenicity than the antigen alone and are considered safer than approaches based on living cells or toxoids.