Kaku Itoh
Sapporo Medical University
10 Papers
16 Citations
Kaku Itoh is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Medicine & Adipogenesis. The author has an hindex of 3, co-authored 5 publications.
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Papers
Prostaglandin F2α Agonists Negatively Modulate the Size of 3D Organoids from Primary Human Orbital Fibroblasts.
TL;DR: 3D tissue culture system may be a suitable strategy for understanding the disease etiology of DUES and indicates that PG analogs have the potential to modulate the ECM network within HOF 3D organoids.
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Prostaglandin F2α agonists induced enhancement in collagen1 expression is involved in the pathogenesis of the deepening of upper eyelid sulcus.
TL;DR: In this paper, the effects of prostaglandin F2α analogues (PGF2α-ags) on human orbital fibroblasts (HOFs) were characterized by lipid staining (2D; two-dimension, 3D), comparison of the 3D organoid sizes of preadipocytes or adipocytes (DIF+) that had been treated with various concentrations of several PGF2α -ags, and physical stiffness (3D), and mRNA expression of adipogenic related genes, extracellular matrix (ECM), tissue inhibitors of
Detection of significantly high vitreous concentrations of fatty acid-binding protein 4 in patients with proliferative diabetic retinopathy.
Kaku Itoh,Masato Furuhashi,Yosuke Ida,Hiroshi Ohguro,Megumi Watanabe,Soma Suzuki,Fumihito Hikage +6 more
TL;DR: In this paper, the levels of V-FABP4 and V-VEGFA were significantly higher in PDR patients than in non-PDR patients (P < 0.001) with a high positive correlation between them.
Fatty acid-binding protein 4 is an independent factor in the pathogenesis of retinal vein occlusion.
Fumihito Hikage,Masato Furuhashi,Yosuke Ida,Hiroshi Ohguro,Megumi Watanabe,Soma Suzuki,Kaku Itoh +6 more
TL;DR: In this paper, the authors identify the fatty acid-binding protein 4 (FABP4) expressed in both adipocytes and macrophages in vitreous fluid from patients with retinal vein occlusion (RVO).
Fatty acid metabolism is involved in both retinal physiology and the pathology of retinal vascular diseases.
Araya Umetsu,Masato Furuhashi,Megumi Watanabe,Ei Ohkawa,Yuri Tsugeno,Soma Suzuki,Kaku Itoh,Yosuke Ida,Fumihito Hikage,Hiroshi Ohguro +9 more
TL;DR: In this paper , the role of the fatty acid-binding proteins (FABPs) within the retina was investigated, and it was shown that V-FAs appear to have significant roles in both retinal physiology and the pathogenesis of RVD with FABP4.
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