Kait F. Al
Lawson Health Research Institute
38 Papers
6 Citations
Kait F. Al is an academic researcher from Lawson Health Research Institute. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 8, co-authored 18 publications. Previous affiliations of Kait F. Al include University of Western Ontario.
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Papers
Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial.
Bertrand Routy,John Lenehan,Wilson H. Miller,Rahima Jamal,Meriem Messaoudene,Brendan A. Daisley,Kait F. Al,Laura Martinez-Gili,Michal Punčochář,Scott Ernst,D M Logan,Karl Belanger,Khashayar Esfahani,Corentin Richard,Marina Ninkov,Gianmarco Piccinno,Federica Armanini,Federica Pinto,M Krishnamoorthy,Rene Figueredo,Pamela Thebault,Panteleimon G. Takis,Jamie Magrill,LeeAnn Ramsay,Lisa Derosa,Julian Marchesi,Seema Nair Parvathy,Arielle Elkrief,Ian R. Watson,Réjean Lapointe,Nicola Segata,S. M. Mansour Haeryfar,Benjamin H. Mullish,Michael Silverman,Jeremy P. Burton,Saman Maleki Vareki +35 more
TL;DR: Fecal microbiota transplantation from healthy donors combined with the anti-PD-1 inhibitors nivolumab or pembrolizumab was well tolerated with an encouraging objective response rate of 65% in the first-line treatment setting.
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Novel probiotic approach to counter Paenibacillus larvae infection in honey bees
Brendan A. Daisley,Andrew P. Pitek,John A. Chmiel,John A. Chmiel,Kait F. Al,Kait F. Al,Anna M. Chernyshova,Kyrillos M. Faragalla,Jeremy P. Burton,Jeremy P. Burton,Graham J. Thompson,Gregor Reid,Gregor Reid +12 more
TL;DR: Findings suggest the usage of a lactobacilli-containing hive supplement, which is practical and affordable for beekeepers, may be effective for reducing enzootic pathogen-related hive losses.
Lactobacillus spp. attenuate antibiotic-induced immune and microbiota dysregulation in honey bees.
Brendan A. Daisley,Brendan A. Daisley,Andrew P. Pitek,John A. Chmiel,John A. Chmiel,Shaeley Gibbons,Anna M. Chernyshova,Kait F. Al,Kait F. Al,Kyrillos M. Faragalla,Jeremy P. Burton,Jeremy P. Burton,Graham J. Thompson,Gregor Reid,Gregor Reid +14 more
- 25 Sep 2020
TL;DR: It is shown that routine antibiotic administration with oxytetracycline selectively increased tetB abundance in the gut microbiota of adult workers while concurrently depleting several key symbionts known to regulate immune function and nutrient metabolism such as Frischella perrera and Lactobacillus Firm-5 strains.
Cutibacterium acnes and the shoulder microbiome.
Boyang Qiu,Kait F. Al,Ana M. Pena-Diaz,George S. Athwal,Darren S. Drosdowech,Kenneth J. Faber,Jeremy P. Burton,David B. O’Gorman +7 more
TL;DR: The presence of a low-abundance microbiome in the rotator cuff and, potentially, in other shoulder tissues is indicated, consistent with the hypothesis that C acnes infections are derived from skin contamination during surgery and not from opportunistic expansion of a resident C Acnes population in the shoulder joint.
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Fecal microbiota transplantation is safe and tolerable in patients with multiple sclerosis: A pilot randomized controlled trial
Kait F. Al,Laura J Craven,Shaeley Gibbons,Seema Nair Parvathy,Ana Christina Wing,Chantelle Graf,Kate A. Parham,Steven M. Kerfoot,Hannah Wilcox,Jeremy P. Burton,M. Kremenchutzky,Sarah A. Morrow,Courtney Casserly,Jon Meddings,Manas Sharma,Michael Silverman +15 more
TL;DR: FMT was safe and tolerable in this cohort of RRMS patients, may improve elevated small intestinal permeability, and has the potential to enrich for an MS-protective microbiota.
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