Kaiman Peng
Australian National University
8 Papers
5 Citations
Kaiman Peng is an academic researcher from Australian National University. The author has contributed to research in topics: Gene expression profiling & Gene expression. The author has an hindex of 5, co-authored 8 publications. Previous affiliations of Kaiman Peng include Monash University, Clayton campus.
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Papers
Enhancement and suppression of signaling by the conserved tail of IgG memory–type B cell antigen receptors
Keisuke Horikawa,Stephen Martin,Sarah L. Pogue,Karlee Silver,Kaiman Peng,Kiyoshi Takatsu,Christopher C. Goodnow +6 more
TL;DR: A novel “less-is-more” hypothesis is suggested to explain how switching to IgG enhances B cell memory responses, whereby decreased BCR signaling to genes that oppose marginal zone and plasma cell differentiation enhances the formation of these key cell types.
APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease
Jorge I. Vélez,Jorge I. Vélez,Francisco Lopera,Diego Sepulveda-Falla,Diego Sepulveda-Falla,Hardip R. Patel,Angad S. Johar,Aaron Chuah,Carlos Tobon,Dora Rivera,Andrés Villegas,Yeping Cai,Kaiman Peng,Ruth M. Arkell,Francisco X. Castellanos,Francisco X. Castellanos,Shea J. Andrews,M F Silva Lara,P K Creagh,Simon Easteal,J. de Leon,Wong Ml,Julio Licinio,Claudio A. Mastronardi,Claudio A. Mastronardi,Mauricio Arcos-Burgos,Mauricio Arcos-Burgos +26 more
TL;DR: This is the first study demonstrating that the APOE*E2 allele modifies the natural history of AD typified by the age of onset in E280A mutation carriers, and is crucial for prediction, follow-up and presumably developing new therapeutic strategies for patients either at risk or affected by AD.
Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome.
Angad S. Johar,Claudio A. Mastronardi,Adriana Rojas-Villarraga,Hardip R. Patel,Aaron Chuah,Kaiman Peng,Angela Higgins,Peter J. Milburn,Stephanie Palmer,Maria Fernanda Silva-Lara,Jorge I. Vélez,Dan Andrews,Matthew A. Field,Gavin A. Huttley,Christopher C. Goodnow,Juan-Manuel Anaya,Mauricio Arcos-Burgos +16 more
TL;DR: Novel and rare exonic mutations that may account for autoimmunity were identified and the LRP1/STAT6 novel mutation has the strongest case for being categorised as potentially causative of MAS given the presence of intriguing patterns of functional interaction with other major genes shaping autoIMmunity.
Optimizing microarray in experimental hypertension
Frances Shannon,Katja U.S. McKenzie,Katja U.S. McKenzie,Amanda J. Edgley,Amanda J. Edgley,Sudha Rao,Sudha Rao,Kaiman Peng,Kaiman Peng,Amany Shweta,Amany Shweta,Chris G Schyvens,Chris G Schyvens,Warwick P Anderson,Warwick P Anderson,Sue Wilson,Sue Wilson,Yvonne Pittelkow,Yvonne Pittelkow,Stephen J. Ohms,Stephen J. Ohms,Judith A. Whitworth,Judith A. Whitworth +22 more
TL;DR: Despite the outbred nature of the rats used in this study, they are useful for gene expression profiling comparisons, andGene expression profiles in the left control kidney were extremely consistent across animals.
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Optimizing microarray in experimental hypertension
Frances Shannon,Katja U.S. McKenzie,Katja U.S. McKenzie,Amanda J. Edgley,Amanda J. Edgley,Sudha Rao,Kaiman Peng,Kaiman Peng,Amany Shweta,Amany Shweta,Chris G Schyvens,Chris G Schyvens,Warwick P Anderson,Warwick P Anderson,Sue Wilson,Sue Wilson,Yvonne Pittelkow,Yvonne Pittelkow,Stephen J. Ohms,Stephen J. Ohms,Judith A. Whitworth,Judith A. Whitworth +21 more
- 01 Jan 2005
TL;DR: In this paper, the level of genetic noise between outbred adult Sprague-Dawley (SD) rats, and the effects of unilateral nephrectomy on changes in gene expression as a basis for the design of microarray studies in experimental hypertension were determined.
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