4 Papers
Kai Guo is an academic researcher from Northeast Agricultural University. The author has contributed to research in topics: Oxidative stress & Nephrotoxicity. The author has an hindex of 4, co-authored 4 publications.
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Papers
Cadmium exposure triggers mitochondrial dysfunction and oxidative stress in chicken (Gallus gallus) kidney via mitochondrial UPR inhibition and Nrf2-mediated antioxidant defense activation.
TL;DR: It is demonstrated that the nephrotoxicity of Cd exposure results in oxidative stress and mitochondrial dysfunction by activating the Nrf2 signaling pathway and inhibiting UPRmt in the kidneys.
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Ameliorative effects of resveratrol against cadmium-induced nephrotoxicity via modulating nuclear xenobiotic receptor response and PINK1/Parkin-mediated Mitophagy.
Qi Zhang,Cong Zhang,Jing Ge,Mei-Wei Lv,Milton Talukder,Milton Talukder,Kai Guo,Yan-Hua Li,Jin-Long Li +8 more
TL;DR: Resveratrol attenuated Cd-induced excessive mitochondrial fission and promoted mitochondrial fusion, which reversed PINK1/Parkin-mediated mitophagy initiation and explicate the potential protection against C d-induced nephrotoxicity and mitochondria damage.
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Comparison of nanoparticle-selenium, selenium-enriched yeast and sodium selenite on the alleviation of cadmium-induced inflammation via NF-kB/IκB pathway in heart
TL;DR: Overall, Se applications, especially Nano-Se, can be most efficiently used for relieving cardiotoxicity by exposed to Cd compared to other Se compound.
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Cadmium induced cardiac inflammation in chicken (Gallus gallus) via modulating cytochrome P450 systems and Nrf2 mediated antioxidant defense.
TL;DR: Findings suggested Cd exposure caused cardiotoxicity through CYP450s enzymes homeostasis disturbance and Nrf2-mediated oxidative stress signal pathways defense and may provide new evidence on molecular mechanism of Cd-induced cardiac toxicity.
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