Ka-Cheuk Liu
Karolinska Institutet
9 Papers
8 Citations
Ka-Cheuk Liu is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Regeneration (biology) & Zebrafish. The author has an hindex of 4, co-authored 6 publications.
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Papers
Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification
Ka-Cheuk Liu,Alethia Villasenor,Maria Bertuzzi,Nicole Schmitner,Niki Radros,Linn Rautio,Kenny Mattonet,Ryota L. Matsuoka,Ryota L. Matsuoka,Sven Reischauer,Sven Reischauer,Didier Y.R. Stainier,Olov Andersson +12 more
TL;DR: In this paper, the role of the vasculature in pancreatic β-cell regeneration was investigated by cross-crossing a zebrafish βcell ablation model into the avascular npas4l mutant (i.e., cloche).
9
IGFBP1 increases b-cell regeneration by promoting a -t ob-cell transdifferentiation
Jing Lu,Ka-Cheuk Liu,Nadja Schulz,Christos Karampelias,Jérémie Charbord,Agneta Hilding,Linn Rautio,Philippe Bertolino,Claes-Göran Östenson,Kerstin Brismar,Olov Andersson +10 more
- 01 Jan 2016
TL;DR: IGFBP1 is identified as an endogenous promoter of b-cell regeneration and its clinical importance in diabetes is highlighted.
7
In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system.
Lianhe Chu,Michishige Terasaki,Charlotte L. Mattsson,Romain Teinturier,Jérémie Charbord,Ercument Dirice,Ka-Cheuk Liu,M.G. Miskelly,Qiao Zhou,Nils Wierup,Rohit N. Kulkarni,Olov Andersson +11 more
TL;DR: In 2018, Boer et al. as discussed by the authors established a high-throughput in vivo chemical screen by using the gip promoter to drive the expression of luciferase in zebrafish.
6
Regenerating insulin-producing β-cells ectopically from a mesodermal origin in the absence of endothelial specification
Ka-Cheuk Liu,Alethia Villasenor,Nicole Schmitner,Niki Radros,Linn Rautio,Sven Reischauer,Didier Y.R. Stainier,Olov Andersson +7 more
TL;DR: In this paper, the role of the vasculature in pancreatic β-cell regeneration was investigated, and it was shown that the vast majority of these ectopic β-cells derived from the mesodermal lineage.
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.
Giorgio Basile,Amedeo Vetere,Jiang Hu,Oluwaseun Ijaduola,Y. Zhang,Ka-Cheuk Liu,Amira M. Eltony,Dario F. De Jesus,Kazuki Fukuda,Colin A. Leech,Oleg G. Chepurny,George G. Holz,Seok Hyun Yun,Olov Andersson,Amit Choudhary,Bridget K. Wagner,Rohit N. Kulkarni +16 more
TL;DR: In this article , the authors found that pancreatic elastase (PE) up-regulated in acinar cells and in islets from Type 1 and Type 2 diabetes patients, and negatively impacts β cell viability.