K. Souckova
8 Papers
47 Citations
K. Souckova is an academic researcher. The author has contributed to research in topics: Cell culture & Gene. The author has an hindex of 2, co-authored 4 publications.
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Papers
Development of IFN-γ resistance is associated with attenuation of SOCS genes induction and constitutive expression of SOCS 3 in melanoma cells
Miloslava Fojtová,V. Boudny,Ales Kovarik,L. Lauerova,L. Adamkova,K. Souckova,Jiri Jarkovsky,J. Kovarik +7 more
TL;DR: The results suggest that progression of melanoma cells from IFN sensitivity to IFN insensitivity associates with changes in SOCS expression, and constitutive expression of SOCS 3 is correlated with attenuation of its induction following IFN treatment.
Strategies for labelling of exogenous and endogenous extracellular vesicles and their application for in vitro and in vivo functional studies
Marie Boudna,Petra Vychytilova-Faltejskova,Tana Machackova,Ondřej Slabý,K. Souckova +4 more
- 09 Mar 2024
TL;DR: This review compiles labelling strategies for extracellular vesicles, including fluorescent, bioluminescent, radioactive, and contrast agents, as well as endogenous mechanisms like Cre-lox and CRISPR-Cas, for in vitro and in vivo functional studies.
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Histology of major organ systems of Nothobranchius fishes: short-lived model species
TL;DR: This overview offers baseline material for comparative histological studies and provides insights into functional and anatomical aspects of organs related to the unique life cycle of Nothobranchius spp.
From fish to cells: Establishment of continuous cell lines from embryos of annual killifish Nothobranchius furzeri and N. kadleci.
K. Souckova,Iva Sovadinova,Alexandr Sember,Eliška Sychrová,Anna Konieczna,Vojtech Bystry,Iva Dyková,Radim Blažek,Karolína Lukšíková,Tomáš Pavlica,Marek Jankásek,Marie Altmanová,Jakub Žák,Martin Reichard,Ondrej Slaby +14 more
TL;DR: In this paper , the establishment and deep characterization of ten continuous cell lines from annual killifish embryos of Nothobranchius and N. kadleci has been reported, and the established cell lines exhibited mostly fibroblast-and epithelial-like morphology and steady growth rates with cell doubling time ranging from 27 to 40 h.
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Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells.
K. Souckova,Ales Kovarik,Ladislav Dušek,L. Humpoliková-Adámková,Lauerová L,E. Krejci,E Matouskova,E Bursikova,Miloslava Fojtová,Kovarík J +9 more
TL;DR: Among the cancer lines, the MDA-MB-468 cells showed increased sensitivity to IFN-gamma and relatively high level of SOCS3 induction (2-3 fold) and there was a good correlation.
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