5 Papers
Juying Han is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Gene & PYCARD. The author has an hindex of 1, co-authored 3 publications.
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Papers
The Upregulation of Integrin αDβ2 (CD11d/CD18) on Inflammatory Macrophages Promotes Macrophage Retention in Vascular Lesions and Development of Atherosclerosis
Moammir Aziz,Kui Cui,Mitali Das,Kathleen E. Brown,Christopher L. Ardell,Maria Febbraio,Elzbieta Pluskota,Juying Han,Huaizhu Wu,Christie M. Ballantyne,Jonathan D. Smith,Martha K. Cathcart,Valentin P. Yakubenko +12 more
TL;DR: The contribution of high densities of CD11d to macrophage arrest during atherogenesis is proved, suggesting thatCD11d/CD18 upregulation on proinflammatory macrophages may represent a common mechanism for macrophAGE retention at inflammatory sites, thereby promoting chronic inflammation and disease development.
Po-02-145 spatial transcriptomics in the human pulmonary vein sleeve
TL;DR: In this paper , spatial transcriptomics was used to identify gene expression in pulmonary vein sections and identify regions where gene expression may be indicative of ectopic pacemaker pathogenesis in the lungs.
Abstract 446: Evaluation Of Zbp1 As An Atherosclerosis Modifier Gene
Jonathan D. Smith,Juying Han +1 more
TL;DR: In this article , the authors identify and validate the candidate gene responsible for the mouse strain effect on atherosclerosis in the Ath28.1.1 -QTL subregion using the Sanger Mouse Genomes Project.
CD6 expression has no effect on atherosclerosis in apolipoprotein E-deficient mice
TL;DR: Loss of CD6 on lymphocytes did not lead to expected reductions in B1a cells and protective IgM levels, and in turn did not alter atherosclerosis in mice, and CD6 deficiency had no effect in both male and female mice on either diet.
Genetic Variant in 3' Untranslated Region of the Mouse Pycard Gene Regulates Inflammasome Activity
TL;DR: In this article, the strongest associated locus mapped very close to the Pycard gene on chromosome 7, which codes for the inflammasome adaptor protein apoptosis-associated speck-like protein containing a CARD (ASC).