Justin M. Balko
Vanderbilt University Medical Center
232 Papers
531 Citations
Justin M. Balko is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Medicine & Breast cancer. The author has an hindex of 54, co-authored 172 publications. Previous affiliations of Justin M. Balko include The Breast Cancer Research Foundation & Vanderbilt University.
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Papers
Impact of adding palbociclib on treatment adherence to ongoing adjuvant endocrine treatment in the global randomized PALLAS randomized trial in patients with early breast cancer.
Eileen Shinn,David Zahrieh,A. DeMichele,N. Zdenkowski,Julie Lemieux,Jun Mao,Vesna Bjelic-Radisic,Michelle J Naughton,Georg Pfeiler,K.A. Gelmon,Justin M. Balko,Daniel Egle,Gabriele Zoppoli,Tiffany A. Traina,M. M. Jimenez,Silvia Antolín Novoa,Tufia C. Haddad,Alistair Ring,A. Wolff,W. Fraser Symmans,J. P. Ponce Lorenzo,Dhanusha Sabanathan,Hal Burstein,Z. Nowecki,Gunda Pristauz-Telsnigg,A. Brufsky,M. Bellet-Ezquerra,Theodoros Foukakis,Y. Novik,G. Rubovszky,Christian F. Singer,Karoline Muehlbacher,Otto Metzger Filho,Theodora Goulioti,Ernest Law,Ann Partridge,Lisa A. Carey,Alexander J. Zoroufy,Dominik Hlauschek,Christian Fesl,E. Mayer,Michael Gnant +41 more
A microRNA gene expression signature predicts response to erlotinib in epithelial cancer cell lines and targets EMT.
J L Bryant,Joel S. Britson,Justin M. Balko,M Willian,R Timmons,Andrey Frolov,Esther P. Black +6 more
TL;DR: It is hypothesised that the tumour microenvironment elicits TGFβ1 and stimulates a miRNA gene expression program that induces resistance to anti-EGFR therapy and drives lung tumour cells to EMT, invasion, and metastasis.
Progesterone receptor-dependent downregulation of MHC class I promotes tumor immune evasion and growth in breast cancer
Julio Tinoco,H. Saunders,Lauryn R. Werner,Xiaopeng Sun,Eilidh I Chowanec,Amanda Heard,Prabhakar Chalise,Jeffery M. Vahrenkamp,Andrea Wilson,Congxiao Liu,Gangjun Lei,Junping Wei,Hugo Cros,Hisham Mohammed,Melissa Troester,C. Perou,Mary A. Markiewicz,Jason Gertz,Justin M. Balko,Zachary C. Hartman,Christy R. Hagan +20 more
Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial.
Radha Rajasingham,Ananta S Bangdiwala,Melanie R. Nicol,Caleb P Skipper,Katelyn A Pastick,Margaret L Axelrod,Matthew F Pullen,Alanna A Nascene,Darlisha A. Williams,Nicole Engen,Elizabeth C Okafor,Brian I. Rini,Ingrid A. Mayer,Emily G. McDonald,Todd C. Lee,Peter Li,Lauren J. MacKenzie,Justin M. Balko,Stephen J. Dunlop,Katherine Huppler Hullsiek,David R. Boulware,Sarah M Lofgren +21 more
TL;DR: Pre-exposure prophylaxis with hydroxychloroquine once or twice weekly did not significantly reduce laboratory-confirmed Covid-19 or Covid -19-compatible illness among healthcare workers.
Trastuzumab Has Preferential Activity against Breast Cancers Driven by HER2 Homodimers
Ritwik Ghosh,Archana Narasanna,Shizhen Emily Wang,Shuying Liu,Anindita Chakrabarty,Justin M. Balko,Ana M. Gonzalez-Angulo,Gordon B. Mills,Elicia Penuel,John Winslow,Jeff Sperinde,Rajiv Dua,Sailaja Pidaparthi,Ali Mukherjee,Kim Leitzel,Wolfgang J. Köstler,Allan Lipton,Michael Bates,Carlos L. Arteaga +18 more
TL;DR: The notion that HER2 oligomeric states regulate HER2 signaling is confirmed, also arguing that trastuzumab sensitivity of homodimers may reflect their inability to activate the PI3K (phosphoinositide 3-kinase)/AKT pathway.