Junyu Chen
Chinese Academy of Sciences
15 Papers
7 Citations
Junyu Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Haloarchaea & Gene. The author has an hindex of 5, co-authored 10 publications.
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Papers
Biodegradation and biocompatibility of haloarchaea-produced poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolymers
TL;DR: Cell biocompatibility of solution-cast films and biodegradation data revealed that haloarchaea-produced R-PHBHV and O-PHbHV copolyesters had a wild range of biodegrading profiles and excellent biOCompatibility, which would have great potential for use in different biomedical applications.
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Abundant Taxa and Favorable Pathways in the Microbiome of Soda-Saline Lakes in Inner Mongolia
Dahe Zhao,Shengjie Zhang,Qiong Xue,Junyu Chen,Jian Zhou,Feiyue Cheng,Ming Li,Yaxin Zhu,Haiying Yu,Songnian Hu,Yanning Zheng,Shuang-Jiang Liu,Hua Xiang +12 more
TL;DR: The microbiome of the brine and sediment samples of nine artificially separated ponds within two soda-saline lakes in Inner Mongolia of China are investigated, indicating that efficient energy regeneration pathway may increase the capacity for environmental adaptation in such saline-alkaline environments.
Prevention of excessive scar formation using nanofibrous meshes made of biodegradable elastomer poly(3-hydroxybutyrate-co-3-hydroxyvalerate).
TL;DR: Results demonstrate that electrospun nanofibrous PHBV meshes mitigate excessive scar formation by regulating myofibroblast formation, showing their promise for use as wound dressings.
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Optimising PHBV biopolymer production in haloarchaea via CRISPRi-mediated redirection of carbon flux.
Lin Lin,Junyu Chen,Ruchira Mitra,Quanxiu Gao,Feiyue Cheng,Tong Xu,Zhenqiang Zuo,Hua Xiang,Jing Han +8 more
- 25 Aug 2021
TL;DR: Lin et al. as mentioned in this paper developed a CRISPR-based interference (CRISPRi) approach that allows to regulate the metabolic pathways related to PHBV synthesis, which can downregulate gene expression in a range of 25% to 98% depending upon the target region.
Deficiency of exopolysaccharides and O-antigen makes Halomonas bluephagenesis self-flocculating and amenable to electrotransformation
TL;DR: In this paper , a CRISPR/Cas9 genome editing tool was optimized using dual-sgRNA strategy to delete large DNA genomic fragments with efficiency of 12.5% for H. bluephagenesis .