Junyi Yang
Sichuan University
8 Papers
60 Citations
Junyi Yang is an academic researcher from Sichuan University. The author has contributed to research in topics: Bioavailability & Pharmacokinetics. The author has an hindex of 4, co-authored 7 publications.
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Papers
Simple quality assessment approach for herbal extracts using high performance liquid chromatography-UV based metabolomics platform.
TL;DR: Results from this study indicated that the proposed HPLC-UV method is reliable for the quality reassessment of some widely used herbal extracts.
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Characterization and evaluation of a self-microemulsifying drug delivery system containing tectorigenin, an isoflavone with low aqueous solubility and poor permeability.
TL;DR: The study implies that SMEDDS containing TG could be an effective strategy for the oral administration of TG, and shows that even the bile duct was ligation, TG-SMEDDS can still keep a better oral bioavailability.
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Preparation, characterization and in vitro/vivo evaluation of tectorigenin solid dispersion with improved dissolution and bioavailability
TL;DR: It is demonstrated that the efficacy of solid dispersions for the enhancement of TG oral bioavailability was by increasing its aqueous solubility and the solid dispersion formulation could be a viable option for enhancing the oral bio availability of TG.
23
Polymer/lipid interplay in altering in vitro supersaturation and plasma concentration of a model poorly soluble drug.
Rui Peng,Jiahao Huang,Li He,Lina Zhao,Cuitong Wang,Wei Wei,Tongchao Xia,Yifei Mao,Yinghui Wen,Ling Wang,Junyi Yang +10 more
TL;DR: Fundamental mechanisms of PVP/PC mixture effect on IND supersaturation and oral bioavailability are revealed, demonstrating that polymer/lipid mixture could be used as a promising carrier to alter supersaturation profile and oralBioavailability of SDDS products.
8
Physicochemical Characterization and Biopharmaceutical Evaluation of ZWF: A Novel Anticancer Drug for the Treatment of Non-small Cell Lung Cancer.
TL;DR: In this paper, the authors evaluated the feasibility of developing ZWF as a form of oral formulation for clinical application based on the principles of biopharmaceutics and pharmacokinetics, and established a fundamental foundation for the development and quality evaluation of the ZWF oral formulations.