Junqiang Yan
Sun Yat-sen University
6 Papers
31 Citations
Junqiang Yan is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Neuroprotection & Parkinson's disease. The author has an hindex of 5, co-authored 5 publications. Previous affiliations of Junqiang Yan include Henan University of Science and Technology.
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Papers
Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease.
TL;DR: The present understandings and concepts underlying the modulation of different receptors in human beings and various experimental models of Alzheimer's disease and Parkinson's disease are recapitulates as well as a conceptual update on the underlying mechanisms.
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The combination of homocysteine and C-reactive protein predicts the outcomes of Chinese patients with Parkinson's disease and vascular parkinsonism.
Limin Zhang,Junqiang Yan,Yunqi Xu,Ling Long,Cansheng Zhu,Xiaohong Chen,Ying Jiang,Lijuan Yang,Lianfang Bian,Qing Wang +9 more
TL;DR: The hypothesis that Hcy and CRP play important roles in the pathogenesis of PD is supported and anti-inflammatory medication could be used in the management of PD and VP.
Melatonin Treatment for Sleep Disorders in Parkinson's Disease: A Meta-Analysis and Systematic Review
TL;DR: It is found that melatonin can significantly improve the subjective and objective sleep quality of patients with PD with good safety and tolerability, and could be considered an effective treatment for insomnia in patients withPD.
Statins: multiple neuroprotective mechanisms in neurodegenerative diseases.
Qing Wang,Junqiang Yan,Xiaohong Chen,Jin Li,Yu Yang,JianPing Weng,Chao Deng,Midori A. Yenari +7 more
TL;DR: The roles of statins in lowering cholesterol, reducing reactive oxygen species, impairing β-amyloid production and serum apolipoprotein E levels, enhancing the levels of endothelial nitric oxide synthase and cerebral blood flow, and modulating cognitive related receptors and matrix metalloproteases are discussed.
Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses
Junqiang Yan,Yunqi Xu,Cansheng Zhu,Limin Zhang,Aimin Wu,Yu Rong Yang,Zhaojun Xiong,Chao Deng,Xu-Feng Huang,Midori A. Yenari,Yuan-Guo Yang,Weihai Ying,Qing Wang,Qing Wang +13 more
TL;DR: Results provide strong evidence that NMDA receptor modulation after simvastatin treatment could partially explain its anxiolytic-like activity and anti-inflammatory mechanisms in experimental parkinsonian models.