Junpeng Gao
Peking University
15 Papers
12 Citations
Junpeng Gao is an academic researcher from Peking University. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 4, co-authored 8 publications. Previous affiliations of Junpeng Gao include Chinese Ministry of Education.
Chat about Author
Papers
Drug repurposing screening and mechanism analysis based on human colorectal cancer organoids.
Yunuo Mao,Wei Wang,Jing-wei Yang,Xin Zhou,Yongqu Lu,Junpeng Gao,Xiao Chen Wang,Lu Wen,Wei Fu,Fuchou Tang +9 more
TL;DR: In this article , a robust organoid-based drug screening system was developed to efficiently identify repurposed drugs for colorectal cancer (CRC) by combining the repused drug library and computation based drug prediction, and 34 drugs with anti-CRC effects were identified.
41
Relationships of tumor differentiation and immune infiltration in gastric cancers revealed by single-cell RNA-seq analyses
Xin Zhou,Jing-wei Yang,Yongqu Lu,Yanpeng Ma,Yan Meng,Qingqing Li,Junpeng Gao,Zhaoyu Jiang,Limei Guo,Wei Wang,Yun Yan Liu,Lu Wen,Miao Kai,Wei Fu,Fuchou Tang +14 more
TL;DR: Wang et al. as mentioned in this paper performed single-cell RNA-sequencing to reveal the relationship between differentiation status of cancer cells and tumor immune microenvironments in gastric cancer, where they identified the signature genes for both DGC and PDGC and found that signature genes of PDGC strongly enriched in the epithelial-mesenchymal transition (EMT) program.
DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor-Dependent Embryonic Stem Cells.
Baojiang Wu,Yunxia Li,Bojiang Li,Baojing Zhang,Yanqiu Wang,Lin Li,Lin Li,Junpeng Gao,Yuting Fu,Shudong Li,Chen Chen,M. Azim Surani,Fuchou Tang,Fuchou Tang,Xihe Li,Siqin Bao +15 more
TL;DR: In this article, the authors show that LIF alone in medium is sufficient for adaptation of 2i/L-ESCs to embryonic stem cells (ESCs) in a hypermethylated state, and they demonstrate that DNA methyltransferases play an important role in LIF-dependent ESC adaptation and self-renewal.
16
Publisher Correction: Single-cell multi-omics sequencing of human early embryos
Lin Li,Fan Guo,Yun Gao,Yixin Ren,Yixin Ren,Peng Yuan,Peng Yuan,Liying Yan,Liying Yan,Rong Li,Rong Li,Ying Lian,Ying Lian,Jingyun Li,Boqiang Hu,Junpeng Gao,Lu Wen,Fuchou Tang,Jie Qiao +18 more
TL;DR: In the version of this Resource originally published, owing to a technical error an incorrect file was used for Supplementary Table 2; this has now been replaced with the correct file.
Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.
Junpeng Gao,Yuxuan Zheng,Yuxuan Zheng,Lin Li,Minjie Lu,Xiangjian Chen,Yu Wang,Yanna Li,Xiaomeng Liu,Yun Gao,Yun Gao,Y. J. Mao,Y. J. Mao,Peng Zhao,Jinan Zhang,Fuchou Tang,Fuchou Tang,Lei Song,Lu Wen,Lu Wen,Jizheng Wang +20 more
TL;DR: This study applied nucleosome occupancy and methylome sequencing, which detected DNA methylation and chromatin accessibility simultaneously, as well as RNA-seq, for multiomics analysis of the 4 chambers of adult and fetal human hearts, and adult mouse hearts, showing conserved region-specific patterns in the mammalian heart.