Juno Lee

TL;DR: Experimental results suggest that the answer is yes: can cellular tolerance against harmful stresses be enhanced by simply forming cell-in-shell hybrid structures, and these hybrids are anticipated to find their applications in various biomedical and bionanotechnological areas.

TL;DR: The chronological progresses in single-cell nanocoating are described, and the historical developments in the field are divided into biotemplating, cytocompatible Nanocoating, and cells in nano-nutshells, depending on the main research focuses.

TL;DR: The cytoprotective coating of physicochemically labile mammalian cells with a durable material has potential applications in cell-based sensors, cell therapy, and regenerative medicine, as well as providing a platform for fundamental single-cell studies in cell biology.

TL;DR: The future direction of this emerging field is explored and it is dictated that the next phase of research should focus on attaining more intricate engineering to achieve stimulus-responsive shell-degradation, multilayer casings with orthogonal functions, and the encapsulation of multiple cells for multicellular artificial spores.