Junlong Wu
Fudan University
64 Papers
119 Citations
Junlong Wu is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 13, co-authored 48 publications. Previous affiliations of Junlong Wu include Shanghai Jiao Tong University.
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Papers
•Journal Article
Genistein exerts multiple suppressive effects on human breast carcinoma cells
Zhimin Shao,Junlong Wu,Z. Shen +2 more
TL;DR: In this article, the suppressive effects of genistein on progression of breast carcinoma were studied in vitro and in vivo, and it was shown that the growth inhibitory effect was associated with increased tumor cell apoptosis, and upregulated p21WAF1/CIP1 expression.
203
Epidemiology and genomics of prostate cancer in Asian men
TL;DR: For example, this article found that prostate cancer incidence varies considerably across different continents, and that the incidence and mortality of prostate cancer have rapidly increased across the continent over the last decade, and substantial differences in epidemiological features have been observed among different Asian regions.
191
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Dalong Cao,Zihao Qi,Yangyang Pang,Haoran Li,Huyang Xie,Junlong Wu,Yongqiang Huang,Yao Zhu,Yijun Shen,Yiping Zhu,Bo Dai,Xin Hu,Dingwei Ye,Ziliang Wang +13 more
TL;DR: It is suggested that RORC-mediated regulation of a PD-L1/ITGB6/FAK/STAT3 signaling axis in bladder cancer provides several potential therapeutic targets to prevent tumor progression.
Germline DNA Repair Gene Mutation Landscape in Chinese Prostate Cancer Patients
Yu Wei,Junlong Wu,Weijie Gu,Xiaojian Qin,Bo Dai,Guowen Lin,Hualei Gan,Stephen J. Freedland,Stephen J. Freedland,Yao Zhu,Dingwei Ye +10 more
TL;DR: This study sequenced germline pathogenic mutations in 18 DNA repair genes in 316 patients and elucidated the mutation landscape of Chinese prostate cancer patients, confirming the necessity of genetic testing in Chinese PCa and calling for a comprehensive analysis in detailed mutation spectra to refine management strategies further, given the ethnic diversity.
59
Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status
Junlong Wu,Guowen Lin,Yao Zhu,Hailiang Zhang,Guohai Shi,Yijun Shen,Yiping Zhu,Bo Dai,Dingwei Ye +8 more
TL;DR: Low expression level of TIM3 in prostate cancer tissues is an independent prognostic factor of poor prognosis for mPCa patients, and also an independent predictor of metastatic castration resistant prostate cancer (mCRPC).