Junichi Ando

Abstract: Disclosed is a compound represented by the general formula: [wherein R1 represents an aryl or heterocyclic group which may be substituted or the like; X1 represents a C2-C4 alkylene group or the like; X2, X3 and X5 independently represent NH, a bond or the like; X4 represents a lower alkylene group, a bond or the like; Y1 represents a bivalent alicyclic hydrocarbon residue which may be substituted or a bivalent alicyclic amine residue which may be substituted; and Z1, Z2, Z3, Z4, Z5 and Z6 independently represent a nitrogen atom, a group represented by the formula: CH, or the like, provided that at least one of Z3, Z4, Z5 and Z6 represents a nitrogen atom] or a salt thereof, which is useful as an antibacterial agent.

TL;DR: A nitrogen-containing heterocyclic compound or pharmaceutically acceptable salt thereof represented by the general formula is a compound which has a potent antibacterial activity and a high safety as discussed by the authors.

TL;DR: In this paper, the authors concerne un compose repondant a la formule generale ci - representee, dans laquelle : R1 represente un groupe aryle ou heterocyclique eventuellement substitue, ou autre ; X 1 represente a groupe alkylene en C2 a C4, O2, X 2, X 3, X 4, X 5, X 6, X 7, X 8, X 9, X 10, X 11, X 12, X 13, X

TL;DR: A nitrogen-containing heterocyclic compound or pharmaceutically acceptable salt thereof represented by the general formula is a compound which has a potent antibacterial activity and a high safety as mentioned in this paper.