Junhui Chen
Peking University
14 Papers
8 Citations
Junhui Chen is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
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Papers
LINC02362 attenuates hepatocellular carcinoma progression through the miR-516b-5p/SOSC2 axis
Dezhi Li,Tao Zhou,Yaqin Li,Yanwei Xu,Xian Zheng,Junhui Chen,Wei Zheng +6 more
TL;DR: It is found that a long non-coding RNA (lncRNA) named LINC02362, whose biological effects have yet to be unveiled in cancers, was associated with a better prognosis in patients with HCC, and might serve as a biomarker for the prognosis of HCC and a promising therapeutic agent for patients withHCC.
Bispecific GPC3/PD-1 CAR-T cells for the treatment of HCC
TL;DR: In this paper , double-target CAR-T cells, targeting glypican-3 (GPC3) and hindering PD-1-PD-L1 binding, were established.
Nucleos(t)ide analogues altered quasispecies composition of hepatitis B virus (HBV)‐resistant mutations in serum HBV DNA and serum HBV RNA
Hao Liao,He Zhang,Jinman Shao,Xiaoyong Li,Wei Zheng,Le Li,Guangxin Yu,Lanlan Si,Tao Zhou,Z. Yao,Jiu-zeng Dai,Dongping Xu,Guanxun Cheng,Jiuxin Qu,Yang Liu,Junhui Chen,Fengmin Lu +16 more
TL;DR: In this paper , the effect of NAs concentration pressure on altering the resistance mutations quasispecies proportion of HBV DNA and HBV RNA in cell supernatant was analyzed in vitro.
14
Exosomes derived from NGF-overexpressing bone marrow mesenchymal stem cell sheet promote spinal cord injury repair in a mouse model
Siqiaozhi Li,Xin Liao,Yixuan He,H. S. Chen,Wei Zheng,Manshu Tang,Xiaohua Guo,Junhui Chen,Sean Hu,Jia Sun +9 more
TL;DR: In this paper , the function of bone marrow mesenchymal stem cells (BMSC) sheet in the progression of spinal cord injury and its underlying mechanism was elucidated, where NGF was highly expressed in the BMSC sheet-loaded Exos and facilitated neuronal differentiation of NSCs and axonal regeneration.
14
Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis
TL;DR: In this article , a study was performed to figure out whether lncRNA SNHG1 was involved in cirrhosis by affecting hepatocyte-like cells (HLC) differentiation of BMSCs.