Junfeng Yan
7 Papers
4 Citations
Junfeng Yan is an academic researcher. The author has contributed to research in topics: Cancer & Cancer research. The author has an hindex of 1, co-authored 1 publications.
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Papers
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Yunben Yang,Lili Li,Chunjing Xu,Yunke Wang,Zhen Wang,Mengyao Chen,Zhou Jiang,Jun Pan,Chenghui Yang,Xiaoqian Li,Kai Song,Junfeng Yan,Wanglan Xie,Xianguo Wu,Zhigang Chen,Ying Yuan,Shu Zheng,Jun Yan,Jian Huang,Fuming Qiu +19 more
TL;DR: The gut microbiota uses LPS as a trigger to regulate MLM accumulation in a chemokine-dependent manner and generate a precancerous inflammatory milieu to facilitate tumourigenesis.
Baicalin enhances the efficacy of 5-Fluorouracil in gastric cancer by promoting ROS-mediated ferroptosis.
TL;DR: The combination of Baicalin and 5-Fu inhibited GC progression and increased intracellular reactive oxygen species (ROS) levels as mentioned in this paper , and the changes in expression of ferroptosis-related genes were validated by qPCR.
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Tumor cell density dependent IL-8 secretion induces the fluctuation of tregs/CD8 + T cells infiltration in hepatocellular carcinoma: one prompt for the existence of density checkpoint
TL;DR: In this article , the authors focused on the response of key immune cell subsets to tumor cell density in hepatocellular carcinoma (HCC) and found that IL-8 mediates this immune fluctuation and promotes the infiltration of Tregs through the DAPK1/pyruvate kinase activity/lactate axis in HCC.
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Levels of oxidative stress in patients with neoadjuvant chemotherapy for gastric cancer: correlation with treatment response
TL;DR: In this paper , the authors investigated the relationship between oxidative stress and treatment response in gastric cancer patients undergoing neoadjuvant chemotherapy and found that patients with an increased antioxidant index after chemotherapy have good treatment responsiveness.
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Special AT‐rich sequence binding protein 1 promotes multidrug resistance in gastric cancer by regulation of Ezrin to alter subcellular localization of ATP‐binding cassette transporters
TL;DR: In this article , the authors found that the high expression of SATB1 in gastric cancer was associated with reduced sensitivity to various chemotherapy drugs, which is a primary factor in the poor response to chemotherapy and subsequent death in Gastric cancer patients.
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