Junfeng Jiang
Second Military Medical University
19 Papers
11 Citations
Junfeng Jiang is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Biology & microRNA. The author has an hindex of 7, co-authored 11 publications.
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Papers
Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling.
Chen Xu,Yan Zhang,Qiaoling Wang,Zhenyu Xu,Junfeng Jiang,Yuping Gao,Minzhi Gao,Jiuhong Kang,Minjuan Wu,Jun Xiong,Kaihong Ji,Wen Yuan,Yue Wang,Houqi Liu +13 more
TL;DR: It is proposed that the above pluripotency factors, GAS5 and NODAL form a feed-forward signalling loop that maintains hESC self-renewal and indicates that the functions of lncRNAs may vary in different cell types due to competing endogenous mechanisms.
BACE1-AS prevents BACE1 mRNA degradation through the sequestration of BACE1-targeting miRNAs
Tao Zeng,Haitao Ni,Yue Yu,Mingke Zhang,Minjuan Wu,Qiaoling Wang,Liujun Wang,Xu Sha,Zhenyu Xu,Chen Xu,Jun Xiong,Junfeng Jiang,Yan Luo,Yue Wang,Houqi Liu +14 more
TL;DR: It is proposed that BACE1 functions as a ceRNA and forms a network through its associations with protein-coding genes, lncRNAs and miRNAs in the pathophysiology of AD.
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Circulating exosomal mRNA profiling identifies novel signatures for the detection of prostate cancer
Jin Ji,Rui Chen,Lin Zhao,Yalong Xu,Zhi Cao,Huan Xu,Xi Chen,Xiaolei Shi,Yasheng Zhu,Ji Lyu,Ji Lyu,Junfeng Jiang,Yue Wang,Tie Zhou,Jingyi He,Xuedong Wei,Jason Boyang Wu,Bo Yang,Fubo Wang +18 more
TL;DR: Wang et al. as mentioned in this paper developed an optimized emRNA detection strategy and identified novel emRNA signatures for the detection of prostate cancer (PCa) associated emRNAs discovered by emRNA-seq in a large cohort of patients.
i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations
Junfeng Jiang,Yuanyuan Chen,Li Zhang,Qishu Jin,Liujun Wang,Shan Xu,Kexin Chen,Li Li,Tao Zeng,Xingfei Fan,Ting-ting Liu,Jiaxin Li,Jinjiang Wang,Chaofeng Han,Fu Gao,Yanyong Yang,Yue Wang +16 more
TL;DR: Wang et al. as discussed by the authors developed a new precise personalized strategy named "i-CRISPR" for cancer treatment through adding DNA damage repair inhibitors(i) and inducing cancer cell-specific DNA double strand breaks by CRISPR.
JAM-A facilitates hair follicle regeneration in alopecia areata through functioning as ceRNA to protect VCAN expression in dermal papilla cells
Minjuan Wu,Chen Xu,Junfeng Jiang,Sha Xu,Jun Xiong,Xiao-Ming Fan,Kaihong Ji,Yunpeng Zhao,Hai-Lai Ni,Yue Wang,Houqi Liu,Zhaofan Xia +11 more
TL;DR: It is proposed that JAM-A 3′ UTR forms a feedback loop with VCAN and miR-221–3p to regulate hDPC maintenance, proliferation, and differentiation, which may lead to developing new therapies for hair loss.