Junfeng Han
Third Military Medical University
10 Papers
109 Citations
Junfeng Han is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Cytotoxic T cell & Antigen. The author has an hindex of 7, co-authored 10 publications.
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Papers
Identification of leukemia-associated antigens in chronic myeloid leukemia by proteomic analysis.
Liyun Zou,Yuzhang Wu,Li Pei,Daping Zhong,Miao Gen,Tingting Zhao,Jiehong Wu,Bing Ni,Zhirong Mou,Junfeng Han,Yongwen Chen,Yi Zhi +11 more
TL;DR: Several new LAAs were identified including alpha enolase, aldolase A, HSP70 protein8, beta-tubulin and tropomyosin isoforms and the detection of autoantibodies in CML may have value on CML screening, diagnosis, or follow-up.
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Efficacy and Safety of a Nanoparticle Therapeutic Vaccine in Patients with Chronic Hepatitis B: A Randomized Clinical Trial.
Lai Wei,Lai Wei,Tingting Zhao,Ji Zhang,Qing Mao,Guozhong Gong,Yongtao Sun,Yongping Chen,Maorong Wang,Deming Tan,Zuojiong Gong,Baosen Li,Junqi Niu,Shu-Chen Li,Huan-Yu Gong,Liyun Zou,Wei Zhou,Zhengcai Jia,Yan Tang,Lei Fei,Yang Hu,Xiaoyun Shang,Junfeng Han,Bei Zhang,Yuzhang Wu +24 more
TL;DR: In this article, a clinical trial was conducted to assess the efficacy and safety of a de novo designed liposome-based nanoparticle lipopeptide vaccine, ePA-44, for chronic hepatitis B (CHB).
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Identification of a new HLA-A*0201-restricted cytotoxic T lymphocyte epitope from CML28
Junfeng Han,Tingting Zhao,Hongli Liu,Zhihua Lin,Huiming Wang,Zhihua Ruan,Liyun Zou,Yuzhang Wu +7 more
TL;DR: It is demonstrated that CML28(173–181) is a naturally processed and presented CTL epitope with HLA-A*0201 motif and has a promising immunogenicity both in vitro and in vivo.
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MHC class I chain-related molecules induced on monocytes by IFN-γ promote NK cell activation
Huiming Wang,Zhihua Ruan,Yiqin Wang,Junfeng Han,Xiaolan Fu,Tingting Zhao,Di Yang,Wenyue Xu,Zhao Yang,Li Wang,Yongwen Chen,Yuzhang Wu +11 more
TL;DR: It is demonstrated here that IFN-gamma exclusively induced or upregulated the expression of MHC class I chain-related (MIC) molecules, which are ligands of the NKG2D receptor, on the surface of human monocytes of the PBMC population.
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Improving the prediction of HLA class I-binding peptides using a supertype-based method.
TL;DR: A supertype-based method was proposed for the modeling of the HLA class I-peptide binding, where candidates of peptides binding to alleles in a given supertypes were screened using the super-motifs, and then the peptidesbinding to specific allele in the supertype were predicted by the model trained on the Supermotif-sharing peptides.
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