Juneth J. Partridge
Scripps Research Institute
6 Papers
61 Citations
Juneth J. Partridge is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Metastasis & Cell. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Juneth J. Partridge include American Red Cross & Memorial Sloan Kettering Cancer Center.
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Papers
Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.
Elena I. Deryugina,Erin M. Conn,Andreas Wortmann,Juneth J. Partridge,Tatyana A. Kupriyanova,Veronica C. Ardi,John D. Hooper,James P. Quigley +7 more
TL;DR: The contribution of CDCP1 to tumor metastasis was analyzed by using HeLa carcinoma cells overexpressing CDBP (HeLa-CDCP1) and a high-disseminating variant of prostate carcinoma PC-3 naturally expressing high levels of CDBP.
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Functional Analysis of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Differentially Expressed by Variants of Human HT-1080 Fibrosarcoma Exhibiting High and Low Levels of Intravasation and Metastasis
Juneth J. Partridge,Mark A. Madsen,Veronica C. Ardi,Thales Papagiannakopoulos,Tatyana A. Kupriyanova,James P. Quigley,Elena I. Deryugina +6 more
TL;DR: Findings demonstrate that tumor-derived MMPs may have protective functions in cancer cell intravasation, i.e. not promoting but rather catalytically interfering with the early stages of cancer dissemination.
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neovascularization induced by growth factors and human tumor cells Proangiogenic role of neutrophil-like inflammatory heterophils during
Elizabeth Hahn-Dantona,James P. Quigley,Elena I. Deryugina,Andries Zijlstra,Marco Seandel,Tatyana A. Kupriyanova,Juneth J. Partridge,Mark A. Madsen +7 more
- 01 Jan 2013
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Unexpected Effect of Matrix Metalloproteinase Down-Regulation on Vascular Intravasation and Metastasis of Human Fibrosarcoma Cells Selected In vivo for High Rates of Dissemination
Elena I. Deryugina,Andries Zijlstra,Juneth J. Partridge,Tatyana A. Kupriyanova,Mark A. Madsen,Thales Papagiannakopoulos,James P. Quigley +6 more
TL;DR: It is determined that HT-hi/diss intravasation was sensitive to a broad-range matrix metalloproteinase (MMP) inhibitor, emphasizing a rising awareness that targeting certain MMPs might result in an enhanced malignancy as this step of the metastatic cascade is dissected and quantified.
Functional role of cell surface CUB domain-containing protein 1 in tumour cell dissemination
Elena I. Deryugina,Erin M. Conn,Andreas Wortmann,Juneth J. Partridge,Tatyana A. Kupriyanova,Veronica C. Ardi,John D. Hooper,James P. Quigley +7 more
- 01 Jan 2009
TL;DR: Findings confirm that CDCP1 functions as an antiapoptotic molecule and indicate that during metastasisCDCP1 facilitates tumor cell survival likely during or soon after extravasation.