June L. Sonnenberg
Roche Institute of Molecular Biology
4 Papers
June L. Sonnenberg is an academic researcher from Roche Institute of Molecular Biology. The author has contributed to research in topics: Transcription factor & Biology. The author has an hindex of 4, co-authored 4 publications.
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Papers
Regulation of Proenkephalin by Fos and Jun
TL;DR: The data suggest that the proenkephalin gene may be a physiological target for Fos and Jun in the hippocampus and indicate that these proto-oncogene transcription factors may play a role in neuronal responses to stimulation.
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Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain.
June L. Sonnenberg,Cathy Mitchelmore,P. F. Macgregor-Leon,J. Hempstead,James I. Morgan,Tom Curran +5 more
TL;DR: Administration of convulsant doses of Metrazole and picrotoxin results in a rapid but transient increase in c‐fos mRNA in mouse brain, which suggests that fos induction might involve stimulation of a glutamate receptor.
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Dynamic alterations occur in the levels and composition of transcription factor AP-1 complexes after seizure
TL;DR: Alterations in the levels and composition of transcription factors may represent one of the molecular mechanisms underlying neuronal adaptation in the brain.