13 Papers
10 Citations
Jun Zhou is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 4, co-authored 13 publications.
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Papers
Comprehensive analysis of the association between tumor glycolysis and immune/inflammation function in breast cancer
Wenhui Li,Ming Xu,Yu Li,Ziwei Huang,Jun Zhou,Qiuyang Zhao,Kehao Le,Fang Dong,Cheng Wan,Peng-Fei Yi +9 more
TL;DR: The enhanced glycolysis activity of breast cancer was associated with pro-tumor immunity, and the interaction between tumor glyCOlysis and immune/inflammation function may be mediated through IL-17 signaling pathway.
SRC Promotes Tamoxifen Resistance in Breast Cancer via Up-Regulating SIRT1
TL;DR: SRC and SIRT1 are both up-regulated in tamoxifen-resistant breast cancer cells and related to a poor prognosis inTamoxifan-treated breast cancer and the interaction between SRC andSIRT1 needs to be further explored.
CXCR4 Antagonist AMD3100 Reverses the Resistance to Tamoxifen in Breast Cancer via Inhibiting AKT Phosphorylation.
Jun Zhou,Kehao Le,Ming Xu,Jie Ming,Wen Yang,Qiulei Zhang,Linlin Lu,Zihan Xi,Shengnan Ruan,Tao Huang +9 more
TL;DR: It is demonstrated that CXCR4 could be a potential prognostic biomarker for tamoxifen-treated breast cancer and the combination of AMD3100 with tamox ifen could beA more efficacious therapeutic strategy for the treatment of tamoxIFen resistance.
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High expression of TRAF4 predicts poor prognosis in tamoxifen-treated breast cancer and promotes tamoxifen resistance.
TL;DR: It is demonstrated that TRAF4 could be a novel prognostic biomarker for tamoxifen-treated breast cancer patients and a potential therapeutic target for tamxifen resistance.
13
MiR-3121-3p promotes tumor invasion and metastasis by suppressing Rap1GAP in papillary thyroid cancer in vitro
Ming Xu,Jun Zhou,Qiulei Zhang,Kehao Le,Zihan Xi,Peng-Fei Yi,Xiangwang Zhao,Jie Tan,Tao Huang +8 more
TL;DR: Rap1GAP expression was suppressed in thyroid cancer compared to adjacent normal tissues and was a potential diagnostic marker of PTC, and its upstream regulator, miR-3121-3p, affects tumor metastasis and proliferation via regulating Rap1G AP expression.