6 Papers
24 Citations
Jun Zhou is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Insulin & Streptozotocin. The author has an hindex of 6, co-authored 6 publications.
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Papers
Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice.
TL;DR: Taken together, RGP can effectively ameliorate hyperglycemia, hyperlipemia, vascular inflammation and oxidative stress in STZ-induced diabetic mice, and thus may be a potential therapeutic option for type 1 diabetes.
109
Selenite exacerbates hepatic insulin resistance in mouse model of type 2 diabetes through oxidative stress-mediated JNK pathway
TL;DR: It is suggested that high-dose selenite treatment exacerbates hepatic insulin resistance in mouse model of type 2 diabetes, at least in part through oxidative stress-mediated JNK pathway, providing new mechanistic insights into the pro-diabetic effect of selenites in type 2 diabetics.
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The preparation and characterization of an antimicrobial polypeptide from the loach, Misgurnus anguillicaudatus.
TL;DR: Similarity searches by comparing amino acid composition, MS-fingerprint, and the N-terminus of MAPP demonstrated that no protein exactly matched MAPP in databases around the world.
29
Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRbeta/IRS-1 and Akt.
Jun Zhou,Kaixun Huang +1 more
TL;DR: New mechanistic insights are provided for the involvement of peroxynitrite in the development of insulin resistance and suggest that nitration of proteins involved in the early steps of insulin signal transduction is a novel molecular mechanism of HFD-induced muscle insulin resistance.
24
Hypoglycemic activity and potential mechanism of a polysaccharide from the loach in streptozotocin-induced diabetic mice
TL;DR: Oral administration of Misgurnus anguillicaudatus polysaccharide (MAP) in streptozotocin-induced diabetic mice suggests that MAP may be a potential therapeutic option for type 1 diabetes.