Jun-Young Kim
Agency for Science, Technology and Research
16 Papers
33 Citations
Jun-Young Kim is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Biofilm & Auxin. The author has an hindex of 8, co-authored 16 publications. Previous affiliations of Jun-Young Kim include Nanyang Technological University & Pohang University of Science and Technology.
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Papers
Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11
Jun-Young Kim,Jun-Young Kim,Jun-Young Kim,Srikanta Sahu,Yin Hoe Yau,Xu Wang,Susana Geifman Shochat,Per Halkjær Nielsen,Per Halkjær Nielsen,Morten Simonsen Dueholm,Daniel E. Otzen,Jungyeol Lee,May Margarette Salido Delos Santos,Joey Kuok Hoong Yam,Nam-Young Kang,Sungjin Park,Haw-Young Kwon,Haw-Young Kwon,Thomas Seviour,Liang Yang,Michael Givskov,Michael Givskov,Young-Tae Chang,Young-Tae Chang +23 more
TL;DR: A novel fluorescent probe, CDy11 (compound of designation yellow 11), is reported, which targets amyloid in the Pseudomonas aeruginosa biofilm matrix through a diversity oriented fluorescent library approach (DOFLA).
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Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target.
Sungjin Park,Beomsue Kim,Sejong Choi,Sivaraman Balasubramaniam,Sung-Chan Lee,Jung Yeol Lee,Heon Seok Kim,Jun-Young Kim,Jong-Jin Kim,Yong-An Lee,Nam-Young Kang,Jin-Soo Kim,Young-Tae Chang,Young-Tae Chang +13 more
TL;DR: A small molecule probe specific for activated macrophages is reported, called CDg16, and its application to visualizing inflammatory atherosclerotic plaques in vivo is demonstrated and used to image atherosclerosis in mice.
Visualizing biofilm by targeting eDNA with long wavelength probe CDr15
Haw-Young Kwon,Jun-Young Kim,Xiao Liu,Jung Yeol Lee,Joey Kuok Hoong Yam,Louise Dahl Hultqvist,Wang Xu,Morten Rybtke,Tim Tolker-Nielsen,Wooseok Heo,Jong-Jin Kim,Nam-Young Kang,Taiha Joo,Liang Yang,Sungjin Park,Michael Givskov,Michael Givskov,Young-Tae Chang,Young-Tae Chang +18 more
TL;DR: Through unbiased screening of bacteria biofilm, a long wavelength probe CDr15 with extracellular DNA as the molecular target revealed a real-time geometric distribution of eDNA in a 3D bacterial colony.
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Forward chemical genetic screening.
TL;DR: A tagged chemical library approach is introduced that significantly facilitates the identification of target proteins and the validation of the target protein, which should include the assessment of target specificity.
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CDy14: a novel biofilm probe targeting exopolysaccharide Psl
Haw-Young Kwon,Jun-Young Kim,Jung Yeol Lee,Joey Kuok Hoong Yam,Louise Dahl Hultqvist,Wang Xu,Morten Rybtke,Tim Tolker-Nielsen,Jong-Jin Kim,Nam-Young Kang,Liang Yang,Sungjin Park,Michael Givskov,Michael Givskov,Young-Tae Chang,Young-Tae Chang +15 more
TL;DR: A novel biofilm detecting fluorescent probe, CDy14, is developed through an unbiased screening of a fluorescence library and elucidated its binding partner Psl, an exopolysaccharide of the biofilm.
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