Jun Yi
Nanjing University
10 Papers
14 Citations
Jun Yi is an academic researcher from Nanjing University. The author has contributed to research in topics: Biology & Gene silencing. The author has an hindex of 10, co-authored 10 publications.
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Papers
MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial–mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma
TL;DR: Re-introduction of QKI-5 expression abrogated the inhibitory effects of miR-143-3p on ESCC cell proliferation and motility, suggesting that miR+3p is a potential therapy for the treatment of ESCC.
Downregulation of MiR-31 stimulates expression of LATS2 via the hippo pathway and promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Yanping Gao,Jun Yi,Kai Zhang,Fan Bai,Bing Feng,Rui Wang,Xiaoyuan Chu,Longbang Chen,Haizhu Song +8 more
TL;DR: It is demonstrated that overexpression of miR-31 undertook an oncogenic role in ESCC by repressing expression of LATS2 via the Hippo Pathway and activating epithelial-mesenchymal transition and could be potential novel molecular markers for predicting the risk of recurrence and prognosis of ESCC.
The Role of Canonical Wnt Signaling in Regulating Radioresistance
TL;DR: Many small-molecule inhibitors that target the Wnt signaling pathway have been identified and shown to promote radiosensitization, and may help to overcome radioresistance in cancer therapy.
MicroRNA-mediated autophagic signaling networks and cancer chemoresistance.
Banzhou Pan,Jun Yi,Haizhu Song +2 more
TL;DR: The recent findings concerning miRNAs involved in autophagy are summarized, mainly focused on the mechanism of miRNA modulation at different autophagic stages, the crucial role ofmiRNAs in the interconnection between autophapy and apoptosis, and the potential of mi RNAs to overcome chemoresistance by targeting autophotic pathways.
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Clinical significance of angiopoietin-like protein 4 expression in tissue and serum of esophageal squamous cell carcinoma patients
TL;DR: Angiopoietin-like protein 4 upregulation may play an important role in ESCC development, and serum ANGPTL4 level may be a potential tumor marker for ESCC diagnosis and prognosis.