Jun Yan
Soochow University (Suzhou)
9 Papers
3 Citations
Jun Yan is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Chemistry & Aptamer. The author has an hindex of 5, co-authored 9 publications.
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Papers
Multifunctional Porous Iron Oxide Nanoagents for MRI and Photothermal/Chemo Synergistic Therapy
Yayun Hu,Hai Hu,Jun Yan,Chao Zhang,Yonggang Li,Mengyun Wang,Weiyi Tan,Jian Liu,Yue Pan,Yue Pan +9 more
TL;DR: Porous hollow Fe3O4 is synthesized as a theranostic agent for MRI and combined photothermal/chemo cancer therapy and it is demonstrated that the porous structure endows the nanoagents an outstanding photothermal property for cancer cell killing, in comparison with other types of iron oxide nanomaterials.
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Effective Drug Carrier Based on Polyethylenimine-Functionalized Bacterial Cellulose with Controllable Release Properties
Xiao Chen,Xuran Xu,Wenping Li,Bianjing Sun,Jun Yan,Chuntao Chen,Jian Liu,Jieshu Qian,Dongping Sun +8 more
- 22 Jun 2018
TL;DR: This work has presented a rational structure design from biomass for controllable drug carrier and exhibited enhanced mechanical strength, remarkable adsorption capacity toward aspirin, BSA, and gentamicin, prolonged and pH-dependent drug release, and low cytotoxicity.
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Aptamer Conformation-Cooperated Enzyme-Assisted Surface-Enhanced Raman Scattering Enabling Ultrasensitive Detection of Cell Surface Protein Biomarkers in Blood Samples
Yingying Li,Qianqian Fang,Xinxing Miao,Xiuyan Zhang,Yun Zhao,Jun Yan,Yiqiu Zhang,Renfei Wu,Baoqing Nie,Michael Hirtz,Jian Liu +10 more
TL;DR: An ultrasensitive biosensor to detect PTK7, an important protein biomarker on the cell surface, by aptamer conformation cooperated enzyme-assisted SERS (ACCESS) technology, which features a synergistic combination of the conformational alteration of the anglerfish aptamer triggered by the recognition of the membrane protein.
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Sensitive detection of antibiotics using aptamer conformation cooperated enzyme-assisted SERS technology.
TL;DR: A methodological development for sensitive detection of antibiotics with aptamer conformation cooperated enzyme-assisted SERS (ACCESS) technology, design and integrate a set of nucleic acid oligos, realizing specific recognition of chloramphenicol and efficient exonuclease III-assisted DNA amplification.
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NIR-Triggered Release of Nitric Oxide with Upconversion Nanoparticles Inhibits Platelet Aggregation in Blood Samples
TL;DR: This work provides a flexible and robust platform to generate cell‐signaling gas molecules trigged by NIR laser with deep tissue penetration and the biological effects of NO releasing are demonstrated by cellular imaging and inhibition of platelet aggregation from blood samples.
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