5 Papers
46 Citations
Jun Wu is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Spinal cord & Spinal cord injury. The author has an hindex of 5, co-authored 5 publications.
Chat about Author
Papers
Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component.
TL;DR: The first murine Trim32 knock-out model (T32KO) is created, which replicates phenotypes of LGMD2H and sarcotubular myopathy and suggests that muscular dystrophy due to TRIM32 mutations involves both neurogenic and myogenic characteristics.
Glial Reactions and Degeneration of Myelinated Processes in Spinal Cord Gray Matter in Chronic Experimental Autoimmune Encephalomyelitis
TL;DR: Co-localization of MBP and the low-affinity neurotrophin receptor, p75, was demonstrated, further supporting the notion of apoptotic oligodendrocyte process degeneration in the gray matter of EAE mice.
23
Glial reactions in a rodent cauda equina injury and repair model.
TL;DR: It is speculated that neuroprotective and axonal growth promoting benefits of the combined glial and microglial/ macrophage responses may outweigh their potential negative effects, as previous studies have shown that implantation of avulsed roots is a successful strategy in promoting reinnervation of peripheral targets.
22
Minocycline protects motor but not autonomic neurons after cauda equina injury.
TL;DR: It is suggested that minocycline may protect degenerating mot oneurons and expand the therapeutic window of opportunity for surgical repair of proximal root lesions affecting spinal motoneurons.
Selective plasticity of primary afferent innervation to the dorsal horn and autonomic nuclei following lumbosacral ventral root avulsion and reimplantation in long term studies.
TL;DR: It is concluded that even remote, efferent root injuries and repair procedures can have an effect on remote and non-lesioned sensory systems sharing common peripheral ganglia.
11