Jun Wang
5 Papers
Jun Wang is an academic researcher. The author has contributed to research in topics: Non-rapid eye movement sleep & Medicine. The author has an hindex of 1, co-authored 5 publications.
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Papers
Multi-modal sequence learning for Alzheimer's disease progression prediction with incomplete variable-length longitudinal data
TL;DR: In this paper , a multi-modal sequence learning framework, highlighted by deep latent representation collaborated sequence learning strategy, is proposed to flexibly handle the incomplete variable-length longitudinal multimodal data.
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0279 Thermoneutral temperature exposure increases slow-wave sleep in the 3xTg-AD mouse model of Alzheimer’s Disease
Jun Wang,Dillon M. Huffman,A Ajwad,Adam D. Bachstetter,Michael Paul Murphy,Bruce F. O'Hara,Marilyn J. Duncan,Sridhar Sunderam +7 more
TL;DR: The feasibility of sleep enhancement through ambient temperature regulation and the effect on amyloid pathology are investigated and it is found that thermoneutral warming caused a significant reduction in both Aβ40 and Aβ42 in the hippocampus, but not in the cortex.
0094 Effects of Rocking-induced Sleep Enhancement on Wild Type (WT) and APPxPS1 Knock-in (KI) Alzheimer’s Disease (AD) Mice
Anjana Subramoniam,Jun Wang,Marilyn J. Duncan,Michael Paul Murphy,Adam D. Bachstetter,Sridhar Sunderam,Bruce F. O’Hara +6 more
TL;DR: In this paper , passive rhythmic movement (rocking) was found to enhance sleep in infants and young wild type (WT) mice, particularly in young WT mice, with the added benefit of being noninvasive, easy to translate for human use, and with negligible side effects.
0225 Effect of thermoneutral temperature exposure in the APP/PS1 knock-in mouse model of Alzheimer’s disease
Jun Wang,Diane Iradukunda,Dillon M. Huffman,Adam D. Bachstetter,Michael Paul Murphy,Bruce F. O’Hara,Marilyn J. Duncan,Sridhar Sunderam +7 more
TL;DR: In this paper, the effect of thermoneutral warming on amyloid pathology is mediated by sleep changes rather than other non-specific physiologic effects of temperature, and the authors conducted a new study on APP/PS1 knock-in (KI) mice.
[Genetic mechanism underlying the resilience to Alzheimer's disease and its prospect for clinical application].
Fan Zeng,Yuhuan Ma,Jun Wang,Yan-Jiang Wang +3 more
- 10 Dec 2022
TL;DR: The most common neurodegenerative disease, Alzheimer's disease (AD) is characterized by progressive cognitive decline and is a major threat to the health of elderly worldwide as mentioned in this paper , and delineation of the protective mechanism of AD is also critical for the etiological treatment.