Jun Wang
Nanjing University
6 Papers
Jun Wang is an academic researcher from Nanjing University. The author has contributed to research in topics: FOXP3 & IL-2 receptor. The author has an hindex of 5, co-authored 6 publications.
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Papers
Regulatory B cell is critical in bone union process through suppressing proinflammatory cytokines and stimulating Foxp3 in Treg cells.
TL;DR: The results support a role of B cell‐mediated regulation early during the bone healing process in patients with normal healing and in DU/NU patients.
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STAT3 promotes bone fracture healing by enhancing the FOXP3 expression and the suppressive function of regulatory T cells.
TL;DR: Stat3 was beneficial to bone fracture healing, possibly by enhancing Treg‐mediated suppression of counteracting inflammations, and suggested that STAT3 could be used as a prognostic marker to identify otherwise undistinguishable patients at risk of developing delayed union or nonunion.
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Comparison of Monolateral External Fixation and Internal Fixation for Skeletal Stabilisation in the Management of Small Tibial Bone Defects following Successful Treatment of Chronic Osteomyelitis
Wang Yicun,Jiang Hui,Zhantao Deng,Jiewen Jin,Jia Meng,Jun Wang,Jianning Zhao,Guojing Sun,Hongbo Qian +8 more
TL;DR: It was relatively safe to use internal fixation for stabilization in osteomyelitis patients whose bone defects were less than 4 cm and infection was well controlled.
Chronic Osteomyelitis Increases the Incidence of Type 2 Diabetes in Humans and Mice.
Wang Yicun,Jun Wang,Zhantao Deng,Jiewen Jin,Jiang Hui,Jia Meng,Haidong Xu,Jianning Zhao,Guojing Sun,Hongbo Qian +9 more
TL;DR: Inflammation, mental illness and lack of exercise were risk factors for the occurrence of T2DM in osteomyelitis in COM patients, and comprehensive consideration of patient history, including metabolism and mental health, is needed in planning future treatment.
LAG-3 Represents a Marker of CD4+ T Cells with Regulatory Activity in Patients with Bone Fracture
Jun Wang,Yunfan Ti,Wang Yicun,Guo Guodong,Jiang Hui,Menghan Chang,Hongbo Qian,Jianning Zhao,Guojing Sun +8 more
TL;DR: The results together suggested that LAG-3 is a marker of CD4+ T cells with regulatory function; at the same time, L AG-3 might have limited the full suppressive potential of Treg cells.
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