37 Papers
60 Citations
Jun Wang is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 17, co-authored 34 publications. Previous affiliations of Jun Wang include Chongqing University.
Chat about Author
Papers
Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop.
Jun Wang,Sen-Lin Xu,Jiang-Jie Duan,Liang Yi,Yu-Feng Guo,Yu Shi,Lin Li,Ze-Yu Yang,Xue-Mei Liao,Jiao Cai,Yan-Qi Zhang,Hualiang Xiao,Li Yin,Hao Wu,Jing-Na Zhang,Sheng-Qing Lv,Qing-Kai Yang,Xiaojun Yang,Tao Jiang,Xia Zhang,Xiu-Wu Bian,Shi-cang Yu +21 more
TL;DR: Evidence is provided indicating that the NOTCH1-SOX2 positive-feedback loop controls GSC invasion along white matter tracts, which exhibited a demyelinated phenotype.
156
Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis.
TL;DR: The outcome of treating two patients with FMT indicates that restoration of the intestinal microbiota barrier can alleviate the infection and modulate the immune response, and warrant further investigation of FMT as a putative new therapy for treating microbiota-related diseases such as MODS.
The role of lysosomes in cancer development and progression.
Tao Tang,Ze-Yu Yang,Di Wang,Xian-yan Yang,Jun Wang,Lin Li,Qian Wen,Lei Gao,Xiu-Wu Bian,Shi-cang Yu +9 more
TL;DR: Identifying the factors and mechanisms that regulate the functional status and spatial distribution of lysosomes and elucidating the relationship between lysOSomes and the development and progression of cancer can provide important information for cancer diagnosis and prognosis prediction and may yield new therapeutic targets.
miRNA-regulated delivery of lincRNA-p21 suppresses β-catenin signaling and tumorigenicity of colorectal cancer stem cells
Jun Wang,Zengjie Lei,Yan Guo,Tao Wang,Zhong-yi Qin,Hualiang Xiao,Li-lin Fan,Dongfeng Chen,Xiu-Wu Bian,Jia Liu,Bin Wang +10 more
TL;DR: It is reported that large intergenic non-coding RNA p21 (lincRNA-p21) is a potent suppressor of stem-like traits of CSCs purified from both primary colorectal cancer tissues and cell lines and application of miR-451 MREs appeared to protect normal liver cells from off-target expression of lincRNAs in both tumor-bearing and naïve mice.
High expression of lysine-specific demethylase 1 correlates with poor prognosis of patients with esophageal squamous cell carcinoma.
Yan-Yan Yu,Bin Wang,Kun Zhang,Zengjie Lei,Yan Guo,Hua-liang Xiao,Jun Wang,Li-lin Fan,Chun-Hui Lan,Yanling Wei,Qiang Ma,Li Lin,Chengyi Mao,Xin Yang,Xiao-di Chen,Yan Li,Yun Bai,Dongfeng Chen +17 more
TL;DR: It is reported that LSD1 expression was elevated in cancerous tissue and correlated with lymph node metastasis and poorer overall survival in patients with ESCC, and suggested that LSD 1 was a potential prognostic maker and may be a molecular target for inhibiting invasion and metastasis in ESCC.
77