Jun Wang
Boston Children's Hospital
7 Papers
15 Citations
Jun Wang is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Enterovirus 71 & Single-nucleotide polymorphism. The author has an hindex of 3, co-authored 7 publications. Previous affiliations of Jun Wang include Xi'an Jiaotong University.
Chat about Author
Papers
N-terminal pro-brain natriuretic peptide levels associated with severe hand, foot and mouth disease
Huiling Deng,Huiling Deng,Yufeng Zhang,Yaping Li,Yu Zhang,Yan Xie,Jun Wang,Xiaoyan Wang,Shuangsuo Dang +8 more
TL;DR: Plasma NT-pro-BNP level appears to be a useful biological marker for predicting the severity and mortality of HFMD with 87 % sensitivity and 86 % specificity.
DNA methylation and SNP in IFITM3 are correlated with hand, foot and mouth disease caused by enterovirus 71.
TL;DR: In this article, the authors explored the mechanisms of interferon-induced transmembrane protein 3 (IFITM3) in response to enterovirus-71-associated hand, foot and mouth disease (EV71-HFMD), in terms of DNA methylation, single-nucleotide polymorphism (SNP) genotype and gene expression.
7
Association of gene polymorphisms of CD55 with susceptibility to and severity of hand, foot, and mouth disease caused by enterovirus 71 in the Han Chinese population.
Mei Li,Yaping Li,Huiling Deng,Huiling Deng,Mu-Qi Wang,Wenjun Wang,Jun Wang,Jun Wang,Feng-Ping Wu,Shuangsuo Dang +9 more
TL;DR: The results suggest that sCD55 expression and the CD55 polymorphism rs2564978 may influence the susceptibility to and severity of EV71 infection.
5
Association of gene polymorphisms of pattern-recognition receptor signaling pathway with the risk and severity of hand, foot, and mouth disease caused by enterovirus 71 in Chinese Han population.
Yaping Li,Mei Li,Xiaoli Jia,Huiling Deng,Huiling Deng,Wenjun Wang,Feng-Ping Wu,Jun Wang,Jun Wang,Shuangsuo Dang +9 more
TL;DR: Findings support an important role of innate immune mechanism in EV71 infection as well as an increased risk of EV71‐induced HFMD in Chinese children, whereas RIG‐1 rs3739674 and TLR3 rs5743305 polymorphisms are associated with disease severity.
The diagnostic yield of intellectual disability: Combined whole genome low-coverage sequencing and medical exome sequencing
TL;DR: There were differences in the diagnostic yields of different variation types among the three ID subgroups, and the single-nucleotide variations showed a higher occurrence rate in the other IDs subgroup.