Jun Peng
Central South University
9 Papers
14 Citations
Jun Peng is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Ischemia. The author has an hindex of 5, co-authored 9 publications.
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Papers
Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion
TL;DR: Intervention of ferroptosis exerts beneficial effects on reperfusion injury but not ischemic injury, laying a basis for precise therapy for patients with myocardial infarction.
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Inhibition of Phosphoglycerate Mutase 5 Reduces Necroptosis in Rat Hearts Following Ischemia/Reperfusion Through Suppression of Dynamin-Related Protein 1
Lang She,Hua Tu,Yin Zhuang Zhang,Li Jing Tang,Nian Sheng Li,Qi Lin Ma,Bin Liu,Qingjie Li,Xiu-Ju Luo,Jun Peng +9 more
TL;DR: Inhibition of PGAM5 can reduce necroptosis in I/R-treated rat hearts through suppression of Drp1; there is a positive feedback between RIPK1 and PG AM5, and PGAM 5 might serve as a novel therapeutic target for prevention of myocardial I/ R injury.
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Suppression of NADPH oxidase attenuates hypoxia-induced dysfunctions of endothelial progenitor cells
TL;DR: It is concluded that NOX-derived ROS contributes to the dysfunctions of EPCs under hypoxic condition and suppression of NOX may provide a novel strategy to improve endothelial functions in hypoxia-relevant diseases.
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Natural compound methyl protodioscin protects rat brain from ischemia/reperfusion injury through regulation of Mul1/SOD2 pathway.
Shu Guo,Yi-Yue Zhang,Jing-Jie Peng,Yue-Qi Li,Wei-Ning Liu,Meng-Xuan Tang,Xiao-Jie Zhang,Jie Yang,Jun Peng,Xiu-Ju Luo +9 more
TL;DR: It is concluded that upregulation of Mul1 in rat brain contributes to cerebral I/R injury via suppression of SOD2 and that MPD protects rat brain from I/r injury through a mechanism involving regulation of Mul 1/SOD2 pathway.
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TMSB4 Overexpression Enhances the Potency of Marrow Mesenchymal Stromal Cells for Myocardial Repair.
Shiyuan Tang,Chengming Fan,Chukwuemeka Daniel Iroegbu,Wenwu Zhou,Zhigong Zhang,Ming Wu,Wangping Chen,Xiaoming Wu,Jun Peng,Zhihong Li,Jinfu Yang +10 more
TL;DR: In this paper, a rat model of myocardial infarction (MI) was used to identify the mechanism of HIF-1α induction by Tβ4 and investigate the effects of bone marrow mesenchymal stromal cells (BMMSCs) transfected with the Tβ 4 gene (TMSB4).
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