Jun Morimoto
Okayama University
19 Papers
7 Citations
Jun Morimoto is an academic researcher from Okayama University. The author has contributed to research in topics: Medicine & Mesenchymal stem cell. The author has an hindex of 6, co-authored 18 publications.
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Papers
Cell therapy for central nervous system disorders: Current obstacles to progress.
Takao Yasuhara,Satoshi Kawauchi,Kyohei Kin,Jun Morimoto,Masahiro Kameda,Tatsuya Sasaki,Brooke Bonsack,Chase Kingsbury,Naoki Tajiri,Cesario V. Borlongan,Isao Date +10 more
TL;DR: The milestone achievements of cell therapy for central nervous system disorders, with equal consideration on the present translational obstacles for clinic application, are described.
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Cell encapsulation enhances antidepressant effect of the mesenchymal stem cells and counteracts depressive-like behavior of treatment-resistant depressed rats
Kyohei Kin,Takao Yasuhara,Masahiro Kameda,Yousuke Tomita,Michiari Umakoshi,Ken Kuwahara,Ittetsu Kin,Naoya Kidani,Jun Morimoto,Mihoko Okazaki,Tatsuya Sasaki,Naoki Tajiri,Naoki Tajiri,Cesario V. Borlongan,Isao Date +14 more
TL;DR: It is suggested that the implantation of eMSCs into the lateral ventricle exerted antidepressant effects likely acting via neurogenic pathways, supporting their utility for depression treatment.
Vagus Nerve Stimulation with Mild Stimulation Intensity Exerts Anti-Inflammatory and Neuroprotective Effects in Parkinson's Disease Model Rats.
Ittetsu Kin,Tatsuya Sasaki,Takao Yasuhara,Masahiro Kameda,Takashi Agari,Mihoko Okazaki,Kakeru Hosomoto,Yosuke Okazaki,Satoru Yabuno,Satoshi Kawauchi,Ken Kuwahara,Jun Morimoto,Kyohei Kin,Michiari Umakoshi,Yousuke Tomita,Naoki Tajiri,Cesario V. Borlongan,Isao Date +17 more
TL;DR: In this article, the authors developed a wireless controllable electrical stimulator to examine the efficacy of Vagus nerve stimulation (VNS) on Parkinson's disease (PD) model rats, and evaluated the therapeutic effects of VNS with behavioral and immunohistochemical outcome assays under different stimulation intensity (0.25, 0.5 and 1 mA).
Hippocampal neurogenesis of Wistar Kyoto rats is congenitally impaired and correlated with stress resistance.
Kyohei Kin,Takao Yasuhara,Masahiro Kameda,Takashi Agari,Tatsuya Sasaki,Jun Morimoto,Mihoko Okazaki,Michiari Umakoshi,Ken Kuwahara,Ittetsu Kin,Naoki Tajiri,Isao Date +11 more
TL;DR: The findings indicate that hippocampal neurogenesis in WKY rats is congenitally impaired in contrast to that in WIS rats, which may be useful for developing new targets for depression treatment.
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Lithium counteracts depressive behavior and augments the treatment effect of selective serotonin reuptake inhibitor in treatment-resistant depressed rats.
Kyohei Kin,Takao Yasuhara,Satoshi Kawauchi,Masahiro Kameda,Kakeru Hosomoto,Yousuke Tomita,Michiari Umakoshi,Ken Kuwahara,Ittetsu Kin,Naoya Kidani,Jun Morimoto,Tatsuya Sasaki,Isao Date +12 more
TL;DR: The results suggest that WKY rats are a promising animal model for treatment-resistant depression, and a new treatment with the same anti-depressive effect as fluoxetine + lithium treatment and fewer side effects compared with lithium would be desirable for patients with treatment- resistant depression.
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