Jun-Li Duan
Shanghai Jiao Tong University
12 Papers
50 Citations
Jun-Li Duan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Vascular endothelial growth factor & Stroke. The author has an hindex of 7, co-authored 12 publications. Previous affiliations of Jun-Li Duan include Chinese Academy of Sciences.
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Papers
ALDH2 protects against stroke by clearing 4-HNE
Jin-Min Guo,Ai-Jun Liu,Pu Zang,Wen-Zhe Dong,Li-ping Ying,Wei-wei Wang,Pu Xu,Xu-Rui Song,Jun Cai,She-Qing Zhang,Jun-Li Duan,Jawahar L. Mehta,Ding-Feng Su +12 more
TL;DR: It is observed that 21 of 1 242 subjects followed for 8 years who developed stroke had higher initial plasma 4-HNE levels than those who did not develop stroke, and activation of the AL DH2 pathway may serve as a useful index in the identification of stroke-prone subjects, and the ALDH2 pathway May be a potential target of therapeutic intervention in stroke.
Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53-dependent pathway
An Hu,Jing-Juan Huang,Jing-Fei Zhang,Wei-Jun Dai,Rui-Lin Li,Zhao-Yang Lu,Jun-Li Duan,Ji-Ping Li,Xiao-Ping Chen,Jing-Ping Fan,Wei-Hua Xu,Hongliang Zheng +11 more
TL;DR: The findings suggest that targeting ATM/Chk2/p53 signal pathway by CUR could be a promising therapeutic approach for HNSCC prevention and therapy.
Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway
Jia Qi,Feng Wang,Ping Yang,X. Wang,Renjie Xu,Jihui Chen,Yanggang Yuan,Zhao-Yang Lu,Jun-Li Duan +8 more
TL;DR: Results suggest that AngII degrades Sirt1 to increase p53 acetylation, which induces Drp1 expression and eventually results in cardiomyocyte apoptosis, which may be a valuable therapeutic target for hypertension induced heart failure.
Arterial Baroreflex Dysfunction Impairs Ischemia-Induced Angiogenesis
Chang-Ning Hao,Chang-Ning Hao,Chang-Ning Hao,Zhen-Hao Huang,Shu-Wei Song,Yi-Qin Shi,Xian Wu Cheng,Toyoaki Murohara,Wei Lu,Ding-Feng Su,Jun-Li Duan,Jun-Li Duan +11 more
TL;DR: ABR dysfunction appears to impair ischemia‐induced angiogenesis through the reduction of eACh/α7‐nAChR‐dependent and ‐independent HIF‐1α/VEGF‐VEGFR2 signaling activation.
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•Journal Article
Rescue of hypertension-related impairment of angiogenesis by therapeutic ultrasound
Zhao-Yang Lu,Rui-Lin Li,Hong-Sheng Zhou,Jing-Juan Huang,Jia Qi,Zhi-Xiao Su,Lan Zhang,Yue Li,Yi-Qin Shi,Chang-Ning Hao,Jun-Li Duan +10 more
TL;DR: The data demonstrated that TUS treatment ameliorated hypertension-related inhibition of ischemia-induced angiogenesis, at least in part, via an NO-dependent manner.
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