11 Papers
95 Citations
Jun Li is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Haplotype & Bipolar disorder. The author has an hindex of 7, co-authored 11 publications. Previous affiliations of Jun Li include Chinese Academy of Sciences.
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Papers
Positive association between the brain-derived neurotrophic factor (BDNF) gene and bipolar disorder in the Han Chinese population
Jie Xu,Yun Liu,Peng Wang,Sheng Li,Sheng Li,Yabing Wang,Jun Li,Daizhan Zhou,Zhuo Chen,Teng Zhao,Ting Wang,He Xu,He Xu,Yifeng Yang,Yifeng Yang,Guoyin Feng,Lin He,Lan Yu,Lan Yu +18 more
TL;DR: The Val66Met polymorphism in a Han Chinese population sample found that the BDNF genotype is associated with BPD in this population, and the data suggested that the Met allele rather than the Val allele increased the risk for B PD in the Han population.
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Positive association between GRIN2B gene and bipolar disorder in the Chinese Han Population
Qian Zhao,Ronglin Che,Zhao Zhang,Peng Wang,Jun Li,You Li,Ke Huang,Wei Tang,Guoyin Feng,Klaus Lindpaintner,Lin He,Lin He,Lin He,Yongyong Shi,Yongyong Shi +14 more
TL;DR: Three single-nucleotide polymorphisms (SNPs) of the GRIN2B gene in a set of 480 unrelated bipolar disorder patients and 480 unrelated genetically matched normal controls were significantly associated, suggesting GRin2B as having a role in the etiology of bipolar disorder.
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Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients.
Zhiyun Wei,Lei Wang,Lei Wang,Jiekun Xuan,Jiekun Xuan,Ronglin Che,Ronglin Che,Jing Du,Shengying Qin,Shengying Qin,Yi Xing,Yi Xing,Bo Gu,Bo Gu,Lun Yang,Lun Yang,Huafang Li,Jun Li,Guoyin Feng,Lin He,Lin He,Lin He,Qinghe Xing,Qinghe Xing +23 more
TL;DR: Variations in the HTR7 gene may not be good genetic markers for predicting the therapeutic efficacy of risperidone, as demonstrated in this study.
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Noncanonical and canonical splice sites: a novel mutation at the rare noncanonical splice-donor cut site (IVS4+1A>G) of SEDL causes variable splicing isoforms in X-linked spondyloepiphyseal dysplasia tarda
Feng Xiong,Jianjun Gao,Jun Li,Yun Liu,Guoyin Feng,Wenli Fang,Hongfen Chang,Jiang Xie,Haitao Zheng,Tingyu Li,Lin He,Lin He +11 more
TL;DR: Disruption of the AT donor site in a rare AT–AC intron, leading to a canonical GT donor site, resulted in a multitude of aberrant transcripts, thus impairing exon definition, and the unexpected splicing patterns resulting from the special mutation provide additional challenges and opportunities for understanding splicing mechanisms and specificity.
A pharmacogenetic study of risperidone on histamine H3 receptor gene (HRH3) in Chinese Han schizophrenia patients.
Zhiyun Wei,Zhiyun Wei,Lei Wang,Lei Wang,Mengmeng Zhang,Mengmeng Zhang,Jiekun Xuan,Jiekun Xuan,Yang Wang,Yang Wang,Baocheng Liu,Baocheng Liu,Liyan Shao,Liyan Shao,Jun Li,Zhen Zeng,Zhen Zeng,Tao Li,Tao Li,Jie Liu,Jie Liu,Ti Wang,Ti Wang,Ming Zhang,Ming Zhang,Shengying Qin,Shengying Qin,Yifeng Xu,Guoyin Feng,Lin He,Lin He,Lin He,Qinghe Xing,Qinghe Xing +33 more
TL;DR: The results demonstrate that polymorphism of the HRH3 gene may be a potential genetic marker for predicting the therapeutic effect of risperidone, and suggest novel pharmacological links betweenHRH3 and ris peridone.
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