Jun Ho Yi
Samsung Medical Center
29 Papers
36 Citations
Jun Ho Yi is an academic researcher from Samsung Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 14 publications. Previous affiliations of Jun Ho Yi include Hanyang University.
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Papers
A phase II study of sunitinib as a second-line treatment in advanced biliary tract carcinoma: a multicentre, multinational study.
Jun Ho Yi,Sumitra Thongprasert,Jeeyun Lee,D.C. Doval,Se Hoon Park,Joon Oh Park,Young Suk Park,Won Ki Kang,Ho Yeong Lim +8 more
TL;DR: This phase II study suggests that sunitinib monotherapy demonstrated marginal efficacy in metastatic BTC patients although toxicity should be concerned in Asian population.
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Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum.
TL;DR: The addition of sunitinib to docetaxel did not significantly prolong TTP, although it significantly increased response, and the overall response rate, disease control rate, overall survival, and toxicity profile were unchanged.
Patient-derived cell models as preclinical tools for genome-directed targeted therapy
Ji Yun Lee,Sun Young Kim,Charny Park,Nayoung K.D. Kim,Jiryeon Jang,Kyunghee Park,Jun Ho Yi,Mineui Hong,Tae-jin Ahn,Oliver Rath,Julia Schueler,Seung Tae Kim,In Gu Do,Su Jin Lee,Se Hoon Park,Yong Ick Ji,Dukwhan Kim,Joon Oh Park,Young Suk Park,Won Ki Kang,Kyoung-Mee Kim,Woong-Yang Park,Ho Yeong Lim,Jeeyun Lee +23 more
TL;DR: Evidence is provided that the patient-derived tumor cell (PDC) model was a promising model for preclinical experiments and closely resembled the patient tumor genome and clinical response.
A prognostic model to predict clinical outcomes with first-line gemcitabine-based chemotherapy in advanced pancreatic cancer.
Jun Ho Yi,Jeeyun Lee,Se Hoon Park,Kyu Taek Lee,Jong Kyun Lee,Kwang Hyuck Lee,Dong Wook Choi,Seong Ho Choi,Jin Seok Heo,Do Hoon Lim,Young Suk Park,Ho Yeong Lim,Won Ki Kang,Keunchil Park,Joon Oh Park +14 more
TL;DR: A prognostic model for advanced pancreatic cancer based on clinical parameters could help to select treatment for patients in clinical practice, and these risk-adapted treatment strategies should be further investigated in prospective studies in such patient populations.
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Anti-tumor efficacy of fulvestrant in estrogen receptor positive gastric cancer
Jun Ho Yi,Ingu Do,Jiryeon Jang,Seung Tae Kim,Kyoung-Mee Kim,Se Hoon Park,Joon Oh Park,Young Suk Park,Ho Yeong Lim,Won Ki Kang,Jeeyun Lee +10 more
TL;DR: Investigating the prognostic role of the estrogen receptor (ER) in gastric cancer patients and suppressing ER by fulvestrant, paclitaxel and ER siRNA showed increased expression of E-cadherin, which is a crucial factor in diffuse-type carcinogenesis.