Julien Calvo
Université Paris-Saclay
33 Papers
110 Citations
Julien Calvo is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Biology & Progenitor cell. The author has an hindex of 15, co-authored 26 publications. Previous affiliations of Julien Calvo include Centre national de la recherche scientifique & International Practical Shooting Confederation.
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Papers
Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells
Dimitris Karamitros,Bilyana Stoilova,Zahra Aboukhalil,Fiona K. Hamey,Andreas Reinisch,Marina Samitsch,Lynn Quek,Georg W. Otto,Emmanouela Repapi,Jessica Doondeea,Batchimeg Usukhbayar,Julien Calvo,Stephen Taylor,Nicolas Goardon,Emmanuelle Six,Françoise Pflumio,Catherine Porcher,Ravindra Majeti,Berthold Göttgens,Paresh Vyas +19 more
TL;DR: It is shown that a continuum of hemopoietic progenitor cells from human cord blood execute lymphoid and myeloid differentiation, rather than only uni-lineage progenitors’ being present downstream of stem cells.
239
NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity
Florence Armstrong,Florence Armstrong,Philippe Brunet de la Grange,Philippe Brunet de la Grange,Bastien Gerby,Bastien Gerby,Marie-Christine Rouyez,Marie-Christine Rouyez,Julien Calvo,Julien Calvo,Michaela Fontenay,Michaela Fontenay,Nicolas Boissel,Hervé Dombret,André Baruchel,Judith Landman-Parker,Paul-Henri Romeo,Paul-Henri Romeo,Paola Ballerini,Françoise Pflumio,Françoise Pflumio +20 more
TL;DR: It is shown that coculture of primary human T-ALL with a mouse stromal cell line expressing the NOTCH ligand delta-like-1 (DL1) reproducibly allowed maintenance of T-LiC and long-term growth of blast cells.
194
Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia
Diego Sánchez-Martínez,Matteo Libero Baroni,Francisco Gutierrez-Agüera,Heleia Roca-Ho,O. Blanch-Lombarte,Sara González-García,Montserrat Torrebadell,Montserrat Torrebadell,Jordi Juncà,Manuel Ramírez-Orellana,Talia Velasco-Hernandez,Clara Bueno,José Luis Fuster,Julia G. Prado,Julien Calvo,Benjamin Uzan,Jan Cools,Mireia Camós,Mireia Camós,Françoise Pflumio,María L. Toribio,Pablo Menendez,Pablo Menendez,Pablo Menendez +23 more
TL;DR: It is reported that the expression of CD1a is mainly restricted to developing cortical thymocytes, and neither CD34+ progenitors nor T cells expressCD1a during ontogeny, confining the risk of on-target/off-tumor toxicity.
119
DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
Laurianne Scourzic,Lucile Couronné,Marianne Terndrup Pedersen,V Della Valle,M'Boyba Diop,Elena Mylonas,Julien Calvo,Enguerran Mouly,Cécile K. Lopez,Cécile K. Lopez,Cécile K. Lopez,N Martin,Michaela Fontenay,Ambre Bender,Sylvain Guibert,Patrice Dubreuil,Philippe Dessen,Nathalie Droin,Françoise Pflumio,Michael Weber,P. Gaulard,P. Gaulard,Kristian Helin,Thomas Mercher,Thomas Mercher,Thomas Mercher,O. Bernard +26 more
TL;DR: The data confirm the transformation potential of DNMT3AR882H Tet2−/− progenitors and represent the first cooperative model in mice involving Tet2 inactivation driving lymphoid malignancies.
70
Dynamics of T-Cell Responses and Memory T Cells during Primary Simian Immunodeficiency Virus Infection in Cynomolgus Macaques
Ingrid Karlsson,Benoit Malleret,Patricia Brochard,Benoit Delache,Julien Calvo,Roger Le Grand,Roger Le Grand,Bruno Vaslin,Bruno Vaslin +8 more
TL;DR: An inverse relationship between plasma viral load and the simian immunodeficiency virus (SIV)-specific T cells responses in peripheral blood and lymph nodes is found and details about the changes of virus-specific immune responses over time are provided.
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