Julian Parkhill
University of Cambridge
788 Papers
3K Citations
Julian Parkhill is an academic researcher from University of Cambridge. The author has contributed to research in topics: Biology & Genome. The author has an hindex of 149, co-authored 759 publications. Previous affiliations of Julian Parkhill include Wellcome Trust Sanger Institute & Wellcome Trust Centre for Human Genetics.
Chat about Author
Papers
Kill and cure: genomic phylogeny and bioactivity of Burkholderia gladioli bacteria capable of pathogenic and beneficial lifestyles.
Cerith Jones,Cerith Jones,Gordon Webster,Alex J. Mullins,Matthew Jenner,Matthew J. Bull,Matthew J. Bull,Yousef Dashti,Yousef Dashti,Theodore Spilker,Julian Parkhill,Julian Parkhill,Thomas R. Connor,John J. LiPuma,Gregory L. Challis,Gregory L. Challis,Eshwar Mahenthiralingam +16 more
- 01 Jan 2021
TL;DR: Burkholderia gladioli is a bacterium with a broad ecology spanning disease in humans, animals and plants, but also encompassing multiple beneficial interactions as mentioned in this paper, including antifungal production exploited by insects to protect their eggs, plant protective abilities and antibiotic biosynthesis.
32
Incidence and characterisation of methicillin-resistant Staphylococcus aureus (MRSA) from nasal colonisation in participants attending a cattle veterinary conference in the UK.
Gavin K. Paterson,Ewan M. Harrison,Emily F. Craven,Andreas Petersen,Anders Rhod Larsen,Matthew J. Ellington,M. Estée Török,M. Estée Török,Sharon J. Peacock,Julian Parkhill,Ruth N. Zadoks,Mark A. Holmes +11 more
TL;DR: The results indicate that recent visitation to a farm is a risk factor for MRSA colonisation and that mecC-MRSA are rare among BCVA delegates (<1% based on sample size), and contact with livestock, including dairy cattle, may still be a risk factors for human colonisation with meCC- MRSA but occurs at a rate below the lower limit of detection available in this study.
Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar
Htin Lin Aung,Htin Lin Aung,Thanda Tun,Danesh Moradigaravand,Claudio U. Köser,Wint Wint Nyunt,Si Thu Aung,Thandar Lwin,Kyi Kyi Thinn,John A. Crump,Julian Parkhill,Sharon J. Peacock,Sharon J. Peacock,Sharon J. Peacock,Gregory M. Cook,Gregory M. Cook,Philip C. Hill +16 more
TL;DR: This is the first whole-genome sequencing study of drug-resistant TB from Myanmar, and introduction of second-line drug susceptibility testing as part of routine diagnosis in Myanmar is needed.
32
•Journal Article
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis (vol 18, pg 729, 2008)
Timothy P. Stinear,Torsten Seemann,Paul Harrison,Grant A. Jenkin,John K. Davies,Paul Dr Johnson,Zahra Abdellah,Claire Arrowsmith,Tracey Chillingworth,Carol Churcher,Kay Clarke,Ann Cronin,Paul Davis,Ian Goodhead,Nancy Holroyd,Kay Jagels,Angela Lord,Sharon Moule,Karen Mungall,Halina Norbertczak,Michael A. Quail,Ester Rabbinowitsch,Danielle Walker,Brian White,Sally Whitehead,P. L. C. Small,Roland Brosch,Lalita Ramakrishnan,Michael A. Fischbach,Julian Parkhill,Stewart T. Cole +30 more
TL;DR: The genome of the M strain of M. marinum comprises a 6,636,827-bp circular chromosome with 5424 CDS, 10 prophages, and a 23-kb mercury-resistance plasmid as discussed by the authors.
32
Induction of bacterial mercury- and copper-responsive promoters: Functional differences between inducible systems and implications for their use in gene-fusions for in vivo metal biosensors
TL;DR: This comparison of induction profiles of PmerTPAD usinglacZ orlux reporter genes, show different stimulus-response curves, probably due to differing instrument sensitivities, which have practical implications in the construction of whole cell gene-fusion biosensors for the detection and quantitation of heavy metals.
30