Julia Proff
University of Erlangen-Nuremberg
6 Papers
10 Citations
Julia Proff is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: T cell & Antigen. The author has an hindex of 5, co-authored 5 publications.
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Papers
Autocrine TNF Is Critical for the Survival of Human Dendritic Cells by Regulating BAK, BCL-2, and FLIPL
Manfred Lehner,Beate Kellert,Julia Proff,Martina Schmid,Philip Diessenbacher,Armin Ensser,Jan Dörrie,Niels Schaft,Martin Leverkus,Eckhart Kämpgen,Wolfgang Holter +10 more
TL;DR: It is demonstrated that the survival of DCs during differentiation and activation depends on autocrine TNF and that the inhibition of BAK plays an important role in this process.
Cytomegalovirus-Infected Cells Resist T Cell Mediated Killing in an HLA-Recognition Independent Manner.
Julia Proff,Christian Walterskirchen,Charlotte U. Brey,René Geyeregger,Florian Full,Armin Ensser,Manfred Lehner,Wolfgang Holter +7 more
TL;DR: The data extend the current knowledge on Betaherpesviral evasion from T cell immunity and show for the first time that, beyond impaired antigen presentation, infected cells are efficiently protected by direct blockade of cytotoxic effector functions through viral proteins.
A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells
Charlotte U. Brey,Julia Proff,Natascha Teufert,Benjamin Salzer,Johannes Brozy,Markus Münz,Jochen Pendzialek,Armin Ensser,Wolfgang Holter,Manfred Lehner +9 more
TL;DR: The functionality of the first BiTE antibody construct targeting an H CMV-encoded glycoprotein for inhibiting HCMV replication in infected cells is proved.
Towards FIB-SEM Based Simulation of Pore-Scale Diffusion in SCR Catalyst Layers
Julia Proff,Matthias Mail,Adrian Lindner,A. Scheuer,M. Bendrich,E. Quinet,Anke Schuler,Torsten Scherer,Christian Kübel,Martin Votsmeier +9 more
TL;DR: In this article , the diffusivity in the upper Cu-Chabazite layer of a dual layer ammonia oxidation catalyst with a lower Pt layer was investigated, where the CO was oxidized in the lower Pt-layer while the upper SCR layer served as an inactive diffusion barrier.
Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection
Manfred Lehner,Gabriel Götz,Julia Proff,Niels Schaft,Jan Dörrie,Florian Full,Armin Ensser,Yves A. Muller,Adelheid Cerwenka,Hinrich Abken,Ornella Parolini,Peter F. Ambros,Heinrich Kovar,Wolfgang Holter +13 more
TL;DR: NKG2D-Ls are defined as targets for a CAR-mediated T cell based immunotherapy of ESFT and a comparison of two different methods of gene transfer reveals strong differences in the susceptibility to ligand-induced receptor down-modulation with possible implications for the applicability of RNA transfection.