Julia Eckenberger
University College Cork
11 Papers
7 Citations
Julia Eckenberger is an academic researcher from University College Cork. The author has contributed to research in topics: Microbiome & Gut flora. The author has an hindex of 2, co-authored 4 publications.
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Papers
Ranking microbiome variance in inflammatory bowel disease: a large longitudinal intercontinental study.
Adam G. Clooney,Julia Eckenberger,Emilio J Laserna-Mendieta,Kathryn A. Sexton,Matthew T Bernstein,Kathy Vagianos,Michael Sargent,Feargal J. Ryan,Carthage Moran,Donal Sheehan,Roy D. Sleator,Roy D. Sleator,Laura E. Targownik,Charles N. Bernstein,Fergus Shanahan,Marcus J. Claesson +15 more
TL;DR: The popular concept of precision medicine and rational design of any therapeutic manipulation of the microbiota will have to contend not only with the heterogeneity of the host response, but also with widely differing lifestyles and with much variance still unaccounted for.
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Machine learning approaches in microbiome research: challenges and best practices
Georgios Papoutsoglou,Sonia Tarazona,Marta B. Lopes,Thomas Klammsteiner,Eliana Ibrahimi,Julia Eckenberger,Pierfrancesco Novielli,Alberto Tonda,Andrea Simeon,Rajesh Shigdel,Stéphane Béreux,Giacomo Vitali,Sabina Tangaro,Leo Lahti,A. Temko,Marcus J. Claesson,Magali Berland +16 more
TL;DR: It is demonstrated that the use of compositional transformations and filtering methods as part of data preprocessing does not always improve the predictive performance of a model, and it is shown how linear modeling by logistic regression coupled with visualization techniques such as Individual Conditional Expectation (ICE) plots can yield interpretable results and offer biological insights.
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Improved gut microbiome recovery following drug therapy is linked to abundance and replication of probiotic strains
Jamie A. FitzGerald,Shriram H. Patel,Julia Eckenberger,Eric Guillemard,Patrick Veiga,Florent Schäfer,J. Walter,Marcus J. Claesson,Muriel Derrien +8 more
TL;DR: Findings show a small but measurable benefit of a fermented milk product on microbiome recovery after antibiotics, which was linked to the detection and replication of specific probiotic strains.
13
Biopsy bacterial signature can predict patient tissue malignancy.
Glenn Hogan,Julia Eckenberger,N. Narayanen,N. Narayanen,Sidney P. Walker,Marcus J. Claesson,Mark Corrigan,Deirdre O'Hanlon,Deirdre O'Hanlon,Mark Tangney +9 more
TL;DR: In this article, the authors used 16S rRNA gene sequencing to identify malignant and non-malignant fresh breast biopsy specimens, collected specifically for this purpose, based on bacterial sequence data alone.
Interactions between Medications and the Gut Microbiome in Inflammatory Bowel Disease
TL;DR: While treatments accounted for a relatively small proportion of the geographic contribution to microbiome variance between Irish and Canadian participants, additive effects from multiple medications contributed significantly to microbiome differences between UC and CD.