Julia E. Geddings
University of North Carolina at Chapel Hill
13 Papers
73 Citations
Julia E. Geddings is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Cancer & Tissue factor. The author has an hindex of 11, co-authored 13 publications.
Chat about Author
Papers
Tumor-derived tissue factor–positive microparticles and venous thrombosis in cancer patients
Julia E. Geddings,Nigel Mackman +1 more
TL;DR: Results suggest that TF-positive MPs may be a useful biomarker to identify patients with cancer who are at high risk for thrombosis.
310
Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer.
Jianguo Wang,Julia E. Geddings,Maria M. Aleman,Jessica C. Cardenas,Pichika Chantrathammachart,Julie C. Williams,Daniel Kirchhofer,Vladimir Y. Bogdanov,Ronald R. Bach,Janusz Rak,Frank C. Church,Alisa S. Wolberg,Rafal Pawlinski,Nigel S. Key,Jen Jen Yeh,Nigel Mackman +15 more
TL;DR: The results of the present study using a xenograft mouse model suggest that tumor TF activates coagulation, whereas TF on circulating MPs may trigger venous thrombosis.
191
Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm
A. Phillip Owens,Todd L. Edwards,Silvio Antoniak,Julia E. Geddings,Eiman Jahangir,Wei-Qi Wei,Joshua C. Denny,Yacine Boulaftali,Wolfgang Bergmeier,Alan Daugherty,Uchechukwu K.A. Sampson,Nigel Mackman +11 more
TL;DR: It is suggested that platelets contribute to abdominal aortic aneurysm progression and rupture.
79
Strengths and weaknesses of a new mouse model of thrombosis induced by inferior vena cava stenosis: communication from the SSC of the ISTH
Julia E. Geddings,Maria M. Aleman,Alisa S. Wolberg,M-L von Brühl,Steffen Massberg,Nigel Mackman +5 more
TL;DR: The strengths and weaknesses of the inferior vena cava (IVC) stenosis mouse model of venous thrombosis are summarized.
44
Comment on "tissue factor expressed by microparticles is associated with mortality but not with thrombosis in cancer patients".
Julia E. Geddings,Nigel Mackman +1 more
TL;DR: Whether elevated TF antigen, TF activity and TF associated to MPs (MPs-TF) are predictive of VTE and mortality in cancer patients is investigated.