Julia Bertolini
Leipzig University
14 Papers
11 Citations
Julia Bertolini is an academic researcher from Leipzig University. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Medicine. The author has an hindex of 9, co-authored 13 publications.
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Papers
The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer.
Gunnar Wichmann,Maciej Rosolowski,Knut Krohn,Markus Kreuz,Andreas Boehm,Anett Reiche,Ulrike Scharrer,Dirk Halama,Julia Bertolini,Ulrike Bauer,Dana Holzinger,Michael Pawlita,Jochen Hess,Christoph Engel,Dirk Hasenclever,Markus Scholz,Peter Ahnert,Holger Kirsten,Alexander Hemprich,Christian Wittekind,Olf Herbarth,Friedemann Horn,Andreas Dietz,Markus Loeffler +23 more
TL;DR: It is found that tumors with transcriptionally inactive HPV16 (DNA+ RNA‐) are similar to HPV‐negative (DNA‐) tumors regarding gene expression and frequency of TP53 mutations and that an immune response‐related gene expression cluster is associated with lymph node metastasis, independent of HPV16 status.
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Therapeutic options for treatment of Merkel cell carcinoma
Kathrin Gessner,Gunnar Wichmann,Andreas Boehm,Anett Reiche,Julia Bertolini,Johannes Brus,Ina Sterker,Stefan Dietzsch,Andreas Dietz +8 more
TL;DR: The different results achieved using cisplatin, docetaxel, and cetuximab led to the conclusion that an individual chemoresponse testing in a predictive short time assay might potentially be a useful diagnostic tool in identifying potentially effective chemotherapy treatments.
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Overexpression of the Hedgehog Signalling Pathway in Head and Neck Squamous Cell Carcinoma
Kamelia Dimitrova,Matthaeus Stoehr,Faramarz Dehghani,Andreas Dietz,Gunnar Wichmann,Julia Bertolini,Christian Mozet +6 more
TL;DR: H pathway overexpression appears to be involved in the initiation of tumour growth and spread due to its stem cell-modulating properties and detection of HH pathway components, and especially Gli1 and SHH, in HNSCC might offer a promising target for further anticancer research.
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Intracranial extension of Schneiderian inverted papilloma: a case report and literature review.
Poramate Pitak-Arnnop,Julia Bertolini,Kittipong Dhanuthai,Jörg Hendricks,Alexander Hemprich,Niels Christian Pausch +5 more
TL;DR: The unusual case of a 72-year-old male patient with inverted papilloma, which fatally extended to the intracranial temporal fossa after multiple recurrences is reported, to the authors’ knowledge, this is the twelfth case in the literature of inverted papilla extending into the temporal Fossa.
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Nitric oxide synthase (NOS2/3) expression in head and neck squamous cell carcinomas in correlation with clinical patterns.
Christian Mozet,Diego G. Marin,Julia Bertolini,Andrea Tannapfel,Gunnar Wichmann,Andreas Dietz +5 more
TL;DR: HNSCCs are able to express both NOS protein isoforms in relevant amounts, and it is presumed that synthesized NO is able to support angiogenetic patterns and facilitate tumor progression and lymphatic spread.
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